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Cytotoxic T cells (CTL) play a central role in the control of viral infections. Their antiviral activity can be mediated by at least two cytotoxic pathways, namely the granule exocytosis pathway, involving perforin and granzymes, and the Fas-FasL pathway. It was shown that the level of Friend retrovirus (FV) replication determines the cytotoxic pathway for(More)
Cytotoxic CD8+ T Lymphocytes (CTL) efficiently control acute virus infections but can become exhausted when a chronic infection develops. Signaling of the inhibitory receptor PD-1 is an important mechanism for the development of virus-specific CD8+ T cell dysfunction. However, it has recently been shown that during the initial phase of infection(More)
The authors would like to correct panel H in Fig 3 to show the correct MFI values of PD-L1 expression on human CD4+ T cells. The error occurred during preparation of the figure for manuscript revision. The percentages of infected CD4 cells expressing PD-L1 were accidentally duplicated from panel I in Fig 3. Please see the corrected version of Fig 3 here.(More)
The Tole of lysine-67 in a class C fl-lactamase is mainly electrostatic Receptor-mediated Mn2+ influx in rat hepatocytes: comparison of cells loaded with Fura-2 ester and cells microinjected with Fura-2 salt Cloning of cDNA encoding the bifunctional dehydroquinase-shikimate dehydrogenase of aromatic-amino-acid biosynthesis in Nicotiana tabacum Research(More)
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