Tanja Riedel

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Previous analyses of possible associations between MHC determinants and cutaneous malignant melanoma (MM) have been inconclusive. We have investigated 98 patients with special emphasis on histologically determined subtypes of MM, and 5 multiple-case families. In addition to HLA-ABC and DR typing, complement allotypes of C2, C4A, C4B, BF were determined.(More)
Little is known on the control of lymphomas by NK cells. Here, we study the role of the NK group 2D (NKG2D) receptor for the immunosurveillance of lymphoma. By using transplantable tumors as well as a λ-myc-transgenic model of endogenously arising lymphoma and NKG2D-deficient mice, we show that NK cells eliminate tumor cells in vivo after receiving two(More)
Costimulatory surface molecules and instructive cytokines expressed by dendritic cells (DCs) determine the outcome of an immune response. In malignant disease, DCs are often functionally compromised. In most tumors studied so far, the deficient induction of effective T cell responses has been associated with a blockade of DC maturation, but little has been(More)
It is well established that an interplay between natural killer (NK) cells and dendritic cells (DCs) gives rise to their reciprocal activation and provides a Th1-biased cytokine milieu that fosters antitumor T-cell responses. Ex vivo-differentiated DCs transferred into mice strongly stimulate endogenous NK cells to produce interferon (IFN)-γ and initiate a(More)
The availability of up-to-date and reliable land cover/use maps is of great importance for many earth science applications. Aim of this study was to systematically analyse the effect of spatial resolution of C-band SAR data on segmentation quality and land cover classification accuracy as well as to find robust SAR parameters for the detection of broad land(More)
The availability of reliable land surface information is crucial for a wide range of applications such as environmental monitoring including essential climate change variables, or agroeconomical aspects for a sustainable land management. Compared to optical remote sensing data, radar sensors can provide datasets with regular coverage of a specific area(More)
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