Tanja N Hofmann

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The purpose of this study was to evaluate the efficiency of radiofrequency tissue volume reduction (RFTVR) and uvulopalatopharyngoplasty (UPPP) in the treatment of snoring in a prospective clinical trial of 79 patients consecutively undergoing surgery for snoring. Seventy-nine patients with primary snoring or mild OSAS (obstructive sleep apnea syndrome)(More)
A normal ciliary beat frequency of ciliated cells is necessary for the mucociliary clearance of the nose and paranasal sinuses. An in vitro investigation was performed to evaluate the influence of topical corticosteroids and antihistamines on the ciliary beat frequency of human nasal mucosa. The nasal sprays examined contained the corticosteroids budesonide(More)
Für eine ungestörte mucociliäre Clearence der Nase und Nasennebenhöhlen ist ein koordinierter Flimmerschlag zilientragender Zellen der Nasenschleimhaut notwendig. Untersucht wurde die Wirkung topischer Kortikosteroide und topischer Antihistaminika auf die Flimmerschlagfrequenz humaner Nasenschleimhaut in vitro. Die 4 getesteten Nasensprays enthielten als(More)
PURPOSE To evaluate whether intraocular tumor-associated lymphangiogenesis contributes to prognosis of ciliary body melanomas with extraocular extension and to study its association with other tumor characteristics. DESIGN Nonrandomized, retrospective case series. PARTICIPANTS Twenty consecutive patients enucleated for a malignant melanoma of the(More)
We investigated the influence of four nasal decongestants and one preservative on ciliated cells, using cell cultures of human nasal mucosa. These cells were exposed to nasal decongestants in vitro. A fast decrease in ciliary beat frequency was seen during naphazoline and oxymethazoline application which was fully reversible after naphazoline. There was(More)
Hintergrund. Seit 4 Jahren stehen verbesserte Endoskope zur Untersuchung der Tränenwege zur Verfügung, woraus der Wunsch nach einer intrakanalikulären und intrasakkalen Therapiemöglichkeit resultierte. Patienten und Methode. Seit September 1997 kam ein KTP-Laser bei Verschlüssen der ableitenden Tränenwege zum Einsatz. Bei Patienten mit einer Stenose zum(More)
OBJECTIVE To assess the functional significance of intraocular tumor-associated lymphatic vessels in ciliary body melanomas with extraocular extension. METHODS Twelve consecutive patients enucleated for a malignant melanoma of the ciliary body with extraocular extension and immunohistochemical presence of intraocular LYVE-1-positive and(More)
The etiology of nasal polyposis is still unknown, although risk factors include Aspirin intolerance, asthma, cystic fibrosis and primary ciliary dyskinesia. We studied frequencies of HLA A, B, DR and DQ in patients with nasal polyposis in order to determine a possible genetic component in the multifactorial pathogenesis of nasal polyps. Previous work has(More)
AIMS To utilise the improved optical qualities of newly developed lacrimal endoscopes and newly miniaturised laser fibres for diagnostic visualisation and laser surgery of the lacrimal system. METHODS A KTP laser (wavelength 532 nm, 10 W energy) was used for laser assisted dacryocystorhinostomy (DCR) with endolacrimal visualisation in 26 patients.(More)
PURPOSE To analyze whether lymphatic vessels can invade the normally alymphatic eye (lymphangiogenesis) in patients with malignant melanoma of the ciliary body with extraocular extension and to correlate these findings with metastasis-free survival. METHODS Ten enucleated globes with the histopathologically and immunohistochemically (S-100, HMB-45, PNL-2,(More)