Tania Peacock

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Clopidogrel is a new oral antiplatelet agent with a structure and mechanism of action similar to ticlopidine; they both block the adenosine diphosphate receptor. Because of better side-effect profile and simpler dosing regime, clopidogrel has largely replaced ticlopidine. In fact, the excellent safety and tolerability profile of clopidogrel compares(More)
Toremifene has antiestrogenic and estrogenic properties in vitro and in vivo. In addition, it may have antiangiogenesis and antimicrotubule properties at higher doses. Studies have demonstrated the efficacy of this agent in the treatment of metastatic breast cancer. We performed a phase II trial of toremifene in patients with androgen-independent prostate(More)
Gastroduodenal injury induced by nonsteroidal anti-inflammatory drugs (NSAIDs) is common. As yet, the ideal means to prevent NSAID-related mucosal injury remains controversial. Antacids are effective agents in treating gastric and duodenal ulcers unrelated to NSAIDs. The aim of this study was to assess the ability of a low-dose antacid to prevent NSAID(More)
Bacterial activity on pesticides can lead to decreased toxicity or persistence in aquatic systems. Rhizosphere activity is difficult to measure in situ. To mimic rhizosphere properties of the soft rush, Juncus effusus, a single-stage gradostat reactor was developed to study cycling of lambda-cyhalothrin by rhizobacteria and the effects of Fe(III) and(More)
P215 Figure 1 Anti-Cancer treatment in PS 0e2, no comorbidities Conclusions Age appears to be an important factor in management decisions in English lung cancer practice. The results indicate that further work is warranted to determine how far the results can be explained by patient preference, appropriate physician judgement and physician prejudice. P216(More)
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