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Low back pain (LBP) is a common health problem and many LBP are caused by lumbar disc degeneration (LDD). ADAMTS-4 (a disintegrin and metalloprotease with thrombospondin motifs-4), also known as aggrecanse-1, plays a core role in degeneration of extracellular matrix in LDD. To investigate the association between ADAMTS-4 genetic polymorphism and LDD, we(More)
STUDY DESIGN A case-control association study was performed to investigate the relationship between LBX1 and adolescent idiopathic scoliosis (AIS) in Northern Chinese Han population. OBJECTIVE To explore the prevalence and functional importance of LBX1 polymorphisms in AIS patients within the Northern Chinese Han population. SUMMARY OF BACKGROUND DATA(More)
For the past century, scientists have developed a variety of methods to evaluate itch and pain in both animal models and human subjects to throw light on some of the most important pathways mediating these unpleasant sensations. Discoveries in the mechanisms underlying itch and pain in both physiological and pathological conditions relied greatly upon these(More)
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