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Oral serum-derived bovine immunoglobulin improves duodenal immune reconstitution and absorption function in patients with HIV enteropathy

• David M. Asmuth, Z Ma, +10 authors Christopher J Miller
• AIDS
• 2013

OBJECTIVES To examine the impact of serum-derived bovine immunoglobulin, an oral medical food known to neutralize bacterial antigen and reduce intestinal inflammation, on restoration of mucosal… (More)

Molecular characterization of stool microbiota in HIV-infected subjects by panbacterial and order-level 16S ribosomal DNA (rDNA) quantification and correlations with immune activation.

• Collin L. Ellis, Z Ma, +14 authors David M. Asmuth
• Journal of acquired immune deficiency syndromes
• 2011

BACKGROUND The relationship between gut microbial community composition at the higher-taxonomic order level and local and systemic immunologic abnormalities in HIV disease may provide insight into… (More)

Gastrointestinal-associated lymphoid tissue immune reconstitution in a randomized clinical trial of raltegravir versus non-nucleoside reverse transcriptase inhibitor-based regimens.

• David M. Asmuth, Z Ma, +8 authors Richard B. Pollard
• AIDS
• 2012

OBJECTIVES To examine immune restoration in duodenal tissue and correlates of reduction of immune activation in chronic HIV-infected patients randomized to different treatment regimens. DESIGN… (More)

Effects of Combined CCR5/Integrase Inhibitors-Based Regimen on Mucosal Immunity in HIV-Infected Patients Naïve to Antiretroviral Therapy: A Pilot Randomized Trial

• Sergio Serrano-Villar, Talía Saínz, +17 authors Guido Silvestri
• PLoS pathogens
• 2016

Whether initiation of antiretroviral therapy (ART) regimens aimed at achieving greater concentrations within gut associated lymphoid tissue (GALT) impacts the level of mucosal immune reconstitution,… (More)

Impact of highly active antiretroviral therapy initiation on CD4(+) T-cell repopulation in duodenal and rectal mucosa.

• Timothy L. Hayes, David M. Asmuth, +7 authors Barbara L Shacklett
• AIDS
• 2013

OBJECTIVE The objective of this study was to assess the effects of HAART initiation on CD4(+) T-cell repopulation and T-cell immune activation in rectal and duodenal mucosa. DESIGN The effects of… (More)

Correction: Effects of Combined CCR5/Integrase Inhibitors-Based Regimen on Mucosal Immunity in HIV-Infected Patients Naïve to Antiretroviral Therapy: A Pilot Randomized Trial

• Sergio Serrano-Villar, Talía Saínz, +16 authors David M. Asmuth
• PLoS pathogens
• 2016

open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author… (More)

Correction: Effects of Combined CCR5/Integrase Inhibitors-Based Regimen on Mucosal Immunity in HIV-Infected Patients Naïve to Antiretroviral Therapy: A Pilot Randomized Trial

• Sergio Serrano-Villar, Talía Saínz, +16 authors David M. Asmuth
• PLoS pathogens
• 2017

[This corrects the article DOI: 10.1371/journal.ppat.1005381.].

Serum-derived bovine immunoglobulin isolate increases peripheral and mucosal CD4 T cell count in patients with HIV enteropathy

• David M. Asmuth, Z Ma, +10 authors Christopher J Miller
• 2013

Track A Basic Science

• David P. Sargeant, Sandeep Deverasetty, +490 authors Scott G. Kitchen
• PloS one
• 2011

Many bioinformatic databases and applications focus on a limited domain of knowledge federating links to information in other databases. This segregated data structure likely limits our ability to… (More)

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