Tammy Dunsmore

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BACKGROUND Pneumonic tularemia is caused by inhalation of the gram negative bacterium, Francisella tularensis. Because of concerns that tularemia could be used as a bioterrorism agent, vaccines and therapeutics are urgently needed. Animal models of pneumonic tularemia with a pathophysiology similar to the human disease are needed to evaluate the efficacy of(More)
Viruses that persist despite seemingly effective antiretroviral treatment (ART) and can reinitiate infection if treatment is stopped preclude definitive treatment of HIV-1 infected individuals, requiring lifelong ART. Among strategies proposed for targeting these viral reservoirs, the premise of the "shock and kill" strategy is to induce expression of(More)
Gamma inulin and Algammulin, two new adjuvants, were examined and compared with alum and Freund's Complete/Incomplete Adjuvant (FCA/FIA), for potentiation of cell-mediated immunity (CMI) and humoral immunity in sheep to a recombinant Taenia ovis antigen. The ability to protect sheep when challenged with live T. ovis eggs was also assessed. The results(More)
TUAB0105LB Figure 1. Cumulative incidence of switch at 3 years of ART by age at start of ART, initial regimen and monitoring strategy by region. 21st International AIDS Conference Abstract Supplement Journal of the International AIDS Society 2016, 19 (Suppl 5) http://www.jiasociety.org/index.php/jias/article/view/21264 |(More)
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