Tamer Mohamed

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We investigated whether plasma long-chain sphingoid base (LCSB) concentrations are altered by transient cardiac ischemia during percutaneous coronary intervention (PCI) in humans and examined the signaling through the sphingosine-1-phosphate (S1P) cascade as a mechanism underlying the S1P cardioprotective effect in cardiac myocytes. Venous samples were(More)
We present OsteoConduct, a novel technology that leverages the human musculoskeletal system to transmit data and interface users in a low-power, secure, non-intrusive fashion. OsteoConduct employs a mechanical stimulus in form of patterned acoustic vibration, generated by human users or external stimulators, and a low-cost receiver, as simple as an(More)
The heart responds to pathological overload through myocyte hypertrophy. Here we show that this response is regulated by cardiac fibroblasts via a paracrine mechanism involving plasma membrane calcium ATPase 4 (PMCA4). Pmca4 deletion in mice, both systemically and specifically in fibroblasts, reduces the hypertrophic response to pressure overload; however,(More)
A phytochemical study of Phlomis thapsoides (Lamiaceae) resulted in the isolation of one new compound, 6,10,17-trimethyl-2-octadecanone, and three known compounds (sitosterol-3-O-β-glucoside, and the iridoid glucosides ipolamiide and lamiide). The structures of the isolated compounds were elucidated using mass spectrometry, 1D/2D NMR spectroscopy(More)
Molecular based devices exhibit favorable electrical characteristics that make them candidates for implementing digital electronic circuits at the nanoscale. Previous work focused on using the crossbar array to implement programmable logic arrays in which hybrid CMOS/nano approaches rely on lithographic scale electronics for signal restoration and(More)
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