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In this paper we present a hardware-accelerated framework and hardware blocks for MPEG-4 part 10 IP-quality assessment. We give examples of various IP-blocks that have been designed and tested on the integration platform. The hardware-accelerated framework enabled us to asses their quality along with the MPEG-4 part 10 software reference model.
AIMS Nitric oxide (NO) plays a pivotal role in the regulation of cardiovascular physiology. Endothelial NO is mainly produced by the endothelial nitric oxide synthase (eNOS) enzyme. eNOS enzymatic activity is regulated at several levels, including Ca(2+)/calmodulin binding and the interaction of eNOS with associated proteins. There is emerging evidence(More)
We investigated whether plasma long-chain sphingoid base (LCSB) concentrations are altered by transient cardiac ischemia during percutaneous coronary intervention (PCI) in humans and examined the signaling through the sphingosine-1-phosphate (S1P) cascade as a mechanism underlying the S1P cardioprotective effect in cardiac myocytes. Venous samples were(More)
We present OsteoConduct, a novel technology that leverages the human musculoskeletal system to transmit data and interface users in a low-power, secure, non-intrusive fashion. OsteoConduct employs a mechanical stimulus in form of patterned acoustic vibration, generated by human users or external stimulators, and a low-cost receiver, as simple as an(More)
BACKGROUND Ras signaling regulates a number of important processes in the heart, including cell growth and hypertrophy. Although it is known that defective Ras signaling is associated with Noonan, Costello, and other syndromes that are characterized by tumor formation and cardiac hypertrophy, little is known about factors that may control it. Here we(More)
The heart responds to pathological overload through myocyte hypertrophy. Here we show that this response is regulated by cardiac fibroblasts via a paracrine mechanism involving plasma membrane calcium ATPase 4 (PMCA4). Pmca4 deletion in mice, both systemically and specifically in fibroblasts, reduces the hypertrophic response to pressure overload; however,(More)
Tissue engineering approaches have the potential to increase the physiologic relevance of human iPS-derived cells, such as cardiomyocytes (iPS-CM). However, forming Engineered Heart Muscle (EHM) typically requires >1 million cells per tissue. Existing miniaturization strategies involve complex approaches not amenable to mass production, limiting the ability(More)
AIMS Tumour necrosis factor-α (TNF-α) plays a key role in the regulation of cardiac contractility. Although cardiomyocytes are known to express the TNF-α receptors (TNFRs), the mechanism of TNF-α signal transmission is incompletely understood. The aim of this study was to investigate whether the tumour suppressor Ras-association domain family protein 1(More)
This paper investigates the possibility of implementing a conventional computing architecture that can practically emulate the functionality of a hypothetical quantum computer. The state of the art transistor feature size makes the resource requirement, for emulating quantum computation with a relatively large number of qubits, possible. In this paperwe(More)
We present TeethClick, a simple yet robust input technique based on automatic detection of teeth clacks with a throat microphone. We address its user interface design and provide results from user studies. TeethClick is intended as an auxiliary input method for hand-free computer operation, especially for people with motor impairments. Compared to(More)