Tamara Brunelli

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Chlamydia trachomatis is the world's most prevalent bacterial sexually transmitted infection and leading infectious cause of blindness, yet it is one of the least understood human pathogens, in part due to the difficulties of in vitro culturing and the lack of available tools for genetic manipulation. Genome sequencing has reinvigorated this field, shedding(More)
-lactamase genes were detected. Bidirectional sequencing of the ull-length KPC and IMP genes was performed as described previusly [2,3]. The PCR products were independently generated twice o characterise the type of KPC and IMP variant. Sequence alignent and analysis were performed online using the BLAST program http://www.ncbi.nlm.nih.gov). DNA sequencing(More)
BACKGROUND The extracellular matrix tissue of the myocardium importantly contributes to left ventricular (LV) performance. Inherited connective tissue disorders related to the FBN1 gene could involve cardiac interstitium resulting in functional abnormalities. HYPOTHESIS To disclose a primary involvement of myocardium, LV function was studied in 28(More)
AIMS The aim of this study was to evaluate (1) homocysteinemia and the prevalence of the C677T MTHFR polymorphism in Marfan patients and (2) whether the severity of cardiovascular manifestations is associated with homocysteinemia and/or C677T polymorphism. METHODS AND RESULTS We studied 107 patients subdivided into three subgroups based on the severity of(More)
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