Talia J Rosenberg

Learn More
Clostridium difficile is a pathogen with increasing severity for which host antibody responses provide protection from disease. DNA vaccination has several advantages compared to traditional vaccine methods, however no study has examined this platform against C. difficile toxins. A synthetic gene was created encoding the receptor-binding domain (RBD) of C.(More)
ADVAX is a DNA-based candidate HIV vaccine that was safe but weakly immunogenic when delivered intramuscularly (IM) in humans. Studies were performed in animal models to determine whether an alternative delivery method, in vivo electroporation (EP), could improve the immunogenicity of ADVAX while maintaining an acceptable safety profile. Immunization of(More)
Experiments were conducted to measure the transportability of radon gas through common concrete samples which were characterized by their mix proportions, dimensions, porosity, air permeability, and radon gas diffusion coefficient. Several innovative test systems and methods were designed, fabricated, and calibrated to accurately measure these radon gas(More)
We describe a new thin-layer chromatography (TLC) method to evaluate the radiochemical purity of 99Tc(m)-tetrofosmin without the drawbacks of toxicity, solvent ratios and time requirement associated with the standard TLC method. The new method uses miniaturized instant TLC plates impregnated with silica gel (ITLCTM/SG, 2.5 x 10 cm) for the stationary phase(More)
In order to reduce the risk of nosocomial infection during endoscopic procedures, a simple, safe and economical technique for disposal of contaminated guide-wires, tubes and catheters is described. A disposable glove, everted over a coiled wire or other endoscopic accessory, creates a pouch which then contains the contaminated object to be discarded. This(More)