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Neural stem cell quiescence is an important feature in invertebrate and mammalian central nervous system development, yet little is known about the mechanisms regulating entry into quiescence, maintenance of cell fate during quiescence, and exit from quiescence. Drosophila neural stem cells (called neuroblasts) provide an excellent model system for(More)
During tissue patterning, developing fields may be subdivided into several non-overlapping domains by region-specific expression of transcription factors. In Drosophila leg development, the most distal segments, the pretarsus and tarsal segment 5 (ta5), are precisely specified by interactions between tarsus homeobox genes (BarH1 and BarH2) and pretarsus(More)
OBJECTIVE To establish a regenerative treatment for soft tissue defects of the external auditory meatus (EAM) without conventional surgical therapy. STUDY DESIGN Controlled clinical pilot study. SETTING General hospitals. PATIENTS Sixty-five patients with new or old EAM defects without active inflammation were selected. Ages ranged from 12 to 87 years(More)
This paper presents an estimation method of the vocal tract spectrum from articulatory movements. The method is based on the interpolation of spectra obtained by phoneme-dependent neural networks. Given the phonemic context and articulation timing corresponding to each phoneme, the proposed method first transforms articulator positions to phoneme-dependent(More)
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