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In Japan, increases in medical costs and decreases in health care personnel are serious national problems. Against this background, an approach called "preventive care," which aims to prevent increases in the number of persons requiring nursing care, received a lot of attention in recent years. This paper proposes a system for preventive care through game(More)
BACKGROUND Endothelin-1 (ET-1) is important in the pathogenesis of systemic sclerosis (SSc). ET-1 binds two receptors, endothelin type A (ETA) and endothelin type B (ETB). Dual ETA/ETB receptor antagonists and a selective ETA receptor antagonist are used clinically to treat SSc, and the effect of these antagonists on fibroblast activation has been(More)
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