Takumi Kawabata

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Blockade of the ERK signaling pathway by ERK kinase (MEK) inhibitors selectively enhances the induction of apoptosis by microtubule inhibitors in tumor cells in which this pathway is constitutively(More)
NKT cells are responsible for hepatitis induced either by concanavalin A (Con-A) or α-galactosylceramide (α-GalCer), and they are also profoundly involved in the generalised Shwartzman reaction (GSR)(More)
PURPOSE The extracellular signal-regulated kinase (ERK) pathway is upregulated in human cancers and represents a target for mechanism-based approaches to cancer treatment. However, specific blockade(More)
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