Takumi Abe

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Calothrixin B, whose structure consists of a pentacyclic indolo[3,2-j]phenanthridine framework, was originally isolated as a secondary metabolite from Calothrix cyanobacteria and was found to exhibit potent antiproliferative activity. In this study, treatment with 100 μM of calothrixin B did not inhibit the proliferation of HL-60 promyelocytic leukemia(More)
AIM To investigate the validity and reliability of a novel performance test, called the "Trail Making Peg" (TMP) test, for evaluating the cognitive function. METHODS We recruited 632 community-dwelling older adults (mean age: 73.3±5.2 years) as subjects for the assessment of the validity of the test and 319 adults (mean age: 73.1±5.2 years) as subjects(More)
Evaluation of the cerebral circulation dynamics in patients with stroke soon after onset is extremely important for planning the optimum treatment. Perfusion computed tomography (CT) was evaluated in 118 patients with stroke within 10 hours of onset in whom initial CT showed no ischemic change. The mean transit time (MTT), cerebral blood flow (CBF), and(More)
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