Taketoshi Sugiyama

Learn More
The authors have previously found that mutant hydra strains showing various types of developmental defects can be isolated through sexual inbreeding of wild hydra. One such defective strain, called nem-4, contains virtually no stenoteles, one of the four types of nematocysts present in hydra, in its tentacles. However, stenoteles are present at a normal(More)
A new T-cell lymphoma cell line, designated T34, was established from freshly isolated lymph node tumor cells of a patient with non-Hodgkin's diffuse large cell lymphoma. The 134 cells, as well as the parental lymphoma cells, showed mature helper/inducer immunopheno-types in that they formed spontaneous sheep erythrocyte rosettes and reacted with OKT-3 and(More)
The asparagine-linked sugar chains obtained from total cell surface membrane glycoproteins of human early myeloblastic leukemic cells (KG-1a cells) were studied. The sugar chains liberated by hydrazinolysis were purified by paper electrophore-sis, paper chromatography, and Bio-Gel P-4 chromatography followed by analysis of exoglycosidase digestion and(More)
A new human urachal adenocarcinoma cell line (KO-BT-1) was estab lished and characterized. It consisted of cuboidal, spindle, and poly morphic giant cells and continued to grow for more than 27 months without contact inhibition. Doubling time was about 15.5 h at the 70th passage. In nude mice the cells produced tumors, the histologies of which were similar(More)
  • T Sugiyama
  • 1995
A single-electrode voltage-clamp technique was employed on in vitro hippocampal slices to investigate the membrane current responsible for the slow afterhyperpolarization (AHP) in CA3 pyramidal cells and the effects of monoamines and antidepressant drugs on this current were studied. This was achieved by using conventional procedure to evoke an AHP in(More)
  • 1