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To identify anthropometrical indices of body fat distribution for predicting the risk of hypertension and diabetes, a population-based prospective study was designed. Subjects in two communities (n = 2,422 and 3,195), who were free of hypertension and diabetes, respectively, were followed-up. The area and gender-specific risk of hypertension and diabetes(More)
This study examined the relationship between perceived adaptation to shift work and shift-related problems. A total of 608 male operators at nuclear power plants completed a set of validated questionnaires including a modified version of the Standard Shiftwork Index, which covered adaptation to shift work, fit to job content, chronotypes, chronic fatigue,(More)
STUDY OBJECTIVES Elevated C-reactive protein (CRP), an inflammatory marker and emerging risk factor for atherosclerosis and coronary heart disease, has been reported in overweight patients with sleep-disordered breathing (SDB). However, the contribution of C-reactive protein to this disease among non-overweight individuals is uncertain. We thus examined the(More)
BACKGROUND AND PURPOSE Limited evidence was available on the metabolic syndrome and risk of cardiovascular disease in Asia. The purpose of this study is to examine the association of the metabolic syndrome and risk of ischemic cardiovascular disease in Japanese men and women. METHODS We conducted an 18-year prospective study of 9087 Japanese people aged(More)
BACKGROUND Epidemiological studies have shown high-sensitive C-reactive protein (hs-CRP) to predict cardiovascular disease. However, there are only limited studies on the effects of hs-CRP levels on risk of stroke especially stroke subtypes. We examined associations of hs-CRP levels with risks of total stroke and its subtypes. METHODS A prospective nested(More)
BACKGROUND Limited data are available on caregiver burden for stroke and dementia patients. We examined the associations of prevalent stroke and dementia with family caregiver burden in Japanese general populations. METHODS A total of 916 Japanese home caregivers, whose family members were covered by long-term care insurance, responded to the caregiver(More)
Subclinical hypothyroidism (SCH) has been associated with type 2 diabetes mellitus. However, it is unknown whether common complications of type 2 diabetes, such as diabetic nephropathy, are also present with SCH. Here, we investigated the association between SCH and diabetic nephropathy among Japanese patients with type 2 diabetes mellitus. In this(More)
Low ankle-arm systolic blood pressure index (AAI) correlates with various cardiovascular risk factors and with risk of subsequent coronary heart disease and stroke in Western countries. However, few epidemiological data are available among Japanese, in whom the reported prevalence of peripheral artery disease is low. We examined the relationship between AAI(More)
Rita F. Redberg, MD Mitchell H. Katz, MD Author Affiliations: Division of Cardiology, University of California, San Francisco (Dr Redberg; redberg@medicine.ucsf.edu); and Department of Health Services, County of Los Angeles, Los Angeles, California (Dr Katz). Dr Redberg is the Editor and Dr Katz is the Deputy Editor of the Archives of Internal Medicine.(More)
BACKGROUND Although associations between snoring and cardiovascular disease have been reported in several prospective studies, there is limited evidence from Asian populations. The objective of this study was to determine if there is an association between self-reported snoring frequency and the incidence of cardiovascular disease in Japanese. METHODS The(More)