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The effects of delta9-tetrahydrocannabinol and 2-arachidonoylglycerol on the intracellular free Ca2+ concentration ([Ca2+]i) in NG108-15 cells were examined in detail. We found that delta9-tetrahydrocannabinol induces a rapid, modest increase in [Ca2+]i. The response was detectable with 3 nM delta9-tetrahydrocannabinol. We also found that very low(More)
Low concentrations of 2-arachidonoylglycerol were found to induce rapid, transient elevation of intracellular free Ca2+ in NG108-15 cells (EC50 was 150 nM). Free arachidonic acid, 2-palmitoylglycerol, 2-oleoylglycerol, 2-linoleoylglycerol and 2-docosahexaenoylglycerol were inactive. Anandamide acted as a partial agonist. Importantly, desensitization was(More)
Dihydropyrimidinase-related protein 2 (DRP-2 or DPYSL-2)mediates the intracellular response to collapsin, a repulsive extracellular guidance cue or axonal outgrowth. DRP-2 is also referred to as collapsin response mediator protein 2 (CRMP-2). We have previously demonstrated that the DRP-2 gene is associated with susceptibility to schizophrenia, but not to(More)
This paper describes multigrain parallel processing on a compiler cooperative chip multiprocessor. The multigrain parallel processing hierarchically exploits multiple grains of parallelism such as coarse grain task parallelism, loop iteration level parallelism and statement level near-fine grain parallelism. The chip multiprocessor has been designed to(More)
In this paper, we propose a scalable and transparent parallelization scheme using threads for multi-core processor. The performance achieved by our scheme is scalable to the number of cores, and the application program is not affected by the actual number of cores. For the performance efficiency, we designed the threads so that they do not suspend and that(More)
Using human permanent teeth, structural and distribution patterns of the surface 'prismless' enamel with the occasional presence of indistinct and/or stunted prism structures were investigated by scanning electron microscopy. The 'prismless' enamel was classified into three shapes: step-like, occurring in mid-coronal enamel; band-like, frequently seen in(More)
New media processing applications such as image recognition and AR (Augment Reality) have become into practical on embedded systems for automotive, digital-consumer and mobile products. Many-core processors have been proposed to realize much higher performance than multi-core processors. We have developed a low-power many-core SoC for multimedia(More)