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BACKGROUND In 2002 the American Thoracic Society/European Respiratory Society (ATS/ERS) classification of idiopathic interstitial pneumonias (IIPs) defined seven specific entities, and provided standardized terminology and diagnostic criteria. In addition, the historical "gold standard" of histologic diagnosis was replaced by a multidisciplinary approach.(More)
Multicentric Castleman disease (MCD) is an atypical lymphoproliferative disorder characterized by systemic lymphadenopathy and constitutional inflammatory symptoms. Dysregulated overproduction of interleukin-6 is responsible for the clinical abnormalities. This multicenter prospective study was undertaken to evaluate the safety and efficacy of a humanized(More)
BACKGROUND It is unclear whether health related quality of life (HRQL) may have a predictive value for mortality in idiopathic pulmonary fibrosis (IPF). We investigated the relationship between HRQL assessed using the St. George's Respiratory Questionnaire (SGRQ) and survival time in patients with IPF, and tried to determine a clinical meaningful cut off(More)
PURPOSE To evaluate the usefulness of a commercially available computer-aided diagnosis (CAD) system that incorporates temporal subtraction for the detection of solitary pulmonary nodules on chest radiographs by readers with different levels of experience. MATERIALS AND METHODS Sixty pairs of chest radiographs in 30 patients with newly detected solitary(More)
A similarity measure for nonrigid volume registration with known joint distribution of a targeted tissue is developed to process tissue slide at the boundaries between the targeted and non-targeted tissues. Pre-segmentation of the targeted tissue is unnecessary. This measure is applied to registering volumes acquired at different time-phases in dynamic CT(More)
BACKGROUND AND PURPOSE We evaluated the effects of varying tube voltage, current per rotation, and section thickness on detectability of 2- and 4-Hounsfield unit (HU) differences on brain CT between normal and ischemic gray matter within 6 hours of ischemia onset, by using a low-contrast phantom. METHODS The phantom with an attenuation of 36 HU(More)
OBJECTIVE The objective of this study was to determine whether the various chronic cystic lung diseases can be differentiated on the basis of the pattern and distribution of abnormalities on high-resolution CT. MATERIALS AND METHODS High-resolution CT scans in 92 patients with chronic cystic lung diseases (18 with pulmonary Langerhans cell histiocytosis,(More)
OBJECTIVE Acute-onset diffuse interstitial lung disease (AoDILD) in patients with rheumatoid arthritis (RA) has been a serious concern, especially for those under treatment with biological agents which may affect the presentation and outcome of AoDILD, including Pneumocystis pneumonia (PCP). Therefore, we conducted a retrospective, multi-center study of(More)
The goals of this study were (1) to evaluate the quality of compressed lung CT images obtained using high resolution CT (HRCT: 2 mm slice thickness) for degree of compression and conventional CT (10 mm slice thickness) images by using physical and subjective evaluations, and (2) to analyze the distortion of density distribution on lung CT images using(More)