Takeru Kusumoto

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Nitrosodimethylamine (NDMA) was detected in the blood, liver and lungs of rats and in the blood of a rabbit, when the animals had been administered aminopyrine and subsequently exposed to nitrogen dioxide in air. The control group not administered aminopyrine (AP) showed no significant amount of NDMA. Dose-effect relationships between the nitrogen dioxide(More)
Geranylgeranoic acid (GGA) and 2,3-dihydrogeranylgeranoic acid (2,3-diGGA) are geranylgeraniol-derived metabolites (Kodaira et al. (2002) J Biochem 132: 327-334). In the present study, we examined the effects of these acids on HL-60 cells. The cells were differentiated into neutrophils by GGA stimulation like retinoic acid stimulation. In the case of cells(More)
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