Takeo Yamamoto

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OBJECTIVES Intense noise exposure having been observed in vicinal areas around the U.S. military airfields in Okinawa, Japan, suggests the possibility of adverse effects on fetal growth, as studies have reported such effects around other airfields. This study analyzes the birth records in Okinawa prefecture and investigates whether lower birth weights of(More)
A synchronous evaluation was performed, using a quick in vivo [2-(14)C]thymidine labeling method, of the toxico- and pharmaco-dynamics of a given dose of yttrium-90 (90Y) at a given time after injection to nude BALB/c mice loaded with 10(7) HuO9 cells. Quantitative data were 14C-microautoradiographs of the liver lobule, intestinal crypts, epiphysial growth(More)
Bendamustine is one of the new key drugs for patients with indolent lymphoma. Bendamustine, together with rituximab, significantly improves the treatment outcomes of these patients. In addition, previous clinical studies have shown the complication rate of severe infection in bendamustine-containing regimens to be relatively low as compared to those of(More)
This paper reports our experience with the digitization project, "Digital Archive of Toyo Bunko Rare Books." The mission of this project is to make rare books accessible to the public through our Web site. This paper describes the image analysis aspect of this project from the viewpoint of digitization workflow, starting from image capture to Web site(More)
Adenosine monophosphate-activated protein kinase (AMPK) is a sensor for cellular energy status. When the cellular energy level is decreased, AMPK is activated and functions to suppress energy-consuming processes, including protein synthesis. Recently, AMPK has received attention as an attractive molecular target for cancer therapy. Several studies have(More)
The hypoxic microenvironment of the bone marrow, known as the hypoxic niche, supports hematopoietic stem cell quiescence and maintains long-term repopulation activity. Hypoxia also affects the expansion of progenitor cells and enhances erythropoiesis and megakaryopoiesis. In contrast to the known effects of hypoxia on normal hematopoiesis, the effects of(More)
This paper briefly describes the basic concepts and current status of portal sites that National Institute of Informatics (NII) is involved in the design and operation for the Digital Silk Roads (DSR) Project. These portal sites aim at disseminating and sharing cultural heritage information related to Silk Roads. This paper introduces two portal sites,(More)
Adult T cell lymphoma-leukemia (ATL) is a highly aggressive disease and allogeneic hematopoietic transplantation (allo-HSCT) is the only therapeutic option for achieving a cure. However, some ATL patients cannot undergo HSCT. One of the important reasons for restricting HSCT in ATL is the high incidence of pulmonary complications associated with ATL(More)
OBJECTIVES To investigate the association between aircraft noise exposure as expressed by Weighted Equivalent Continuous Perceived Noise Level (WECPNL) and preschool children's misbehaviours around the Kadena and Futenma airfields in Okinawa. METHODS A questionnaire survey on children's misbehaviour was conducted in nursery schools and kindergartens(More)
We point out a possibility of the weak universality of spin-glass phase transitions in three dimensions. The Ising, the XY, and the Heisenberg models with ±J bond distributions undergo finite-temperature phase transitions with a ratio of critical exponents γ/ν = 2.4. Evaluated critical exponents agree with corresponding experimental results. The analyses(More)