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- Takeharu Ono, Jun Mimuro, +6 authors Yoichi Sakata
- Blood
- 2006
Deficiency of ADAMTS13 is found in patients with thrombotic thrombocytopenic purpura (TTP), and the genetic defects in the ADAMTS13 gene or the autoantibody against ADAMTS13 is thought to be… (More)
- Seiji Madoiwa, Shin Nunomiya, +4 authors Yoichi Sakata
- International journal of hematology
- 2006
Sepsis-induced disseminated intravascular coagulation (DIC) is a serious condition because it is closely linked to the development of multiple organ dysfunctions. We compared molecular fibrinolysis… (More)
- Shotaro Taniguchi, Teruto Hashiguchi, +9 authors Ikuro Maruyama
- Thrombosis research
- 2010
INTRODUCTION
Deficiency of Von Willebrand factor (VWF)-cleaving protease (ADAMTS13) causes platelet thrombosis in the microcirculation. Intrarenal coagulation is thought to be associated with the… (More)
- Nobuyuki Tai, Kenji Kuwabara, +6 authors Yuichi Hori
- Inflammation Research
- 2009
The aim of this study is to verify the crucial role of cytosolic phospholipase A2 alpha (cPLA2 alpha) in the pathogenesis of collagen-induced arthritis in mice and to determine the anti-arthritic… (More)
- Jun Mimuro, Masanori Niimura, +7 authors Yoichi Sakata
- Thrombosis research
- 2008
INTRODUCTION
Secondary ADAMTS13 deficiency may occur in septic patients. The expression of ADAMTS13 in mouse endotoxinemia was studied.
METHODS
The blood and mRNA expression levels of ADAMTS13 and… (More)
- Akiei Hamano, Jun Mimuro, +12 authors Yoichi Sakata
- Blood
- 2004
Thrombophilic dysfibrinogen Tokyo V was identified in a 43-year-old man with recurrent thromboembolism. Based on analyses of the patient fibrinogen genes, the amino acid sequence of the aberrant… (More)
- Ulrike Schweiger-Hufnagel, Takeharu Ono, +10 authors Hidetoshi Okuyama
- Biotechnology Letters
- 2004
A water-insoluble, extracellular polysaccharide was isolated from the culture medium of the snow mold fungus, Microdochium nivale, that had been cultivated in potato/dextrose broth. The… (More)
- Kenichiro Enooku, Reiko Kato, +8 authors Yutaka Yatomi
- Clinica chimica acta; international journal of…
- 2013
BACKGROUND
Although a defect in ADAMTS13 activity is known to cause platelet thrombosis resulting in thrombotic thrombocytopenic purpura (TTP), recent evidence has revealed that low plasma ADAMTS13… (More)
- Shun-ichi Chitose, Takahiko Sakazaki, Takeharu Ono, Takashi Kurita, Hiroyuki Mihashi, Tadashi Nakashima
- The Journal of laryngology and otology
- 2010
OBJECTIVE
This study aimed to clarify the local immune status in the larynx in the presence of infection or carcinogenesis associated with human papilloma virus.
METHODS
Cytological samples (for… (More)
- Kunio Torii, Hideki Kimura, +7 authors Haruyoshi Yoshida
- Rinsho byori. The Japanese journal of clinical…
- 2004
Plasminogen activator inhibitor-1 (PAI-1) may contribute to renal fibrosis because of its involvement in matrix (ECM) accumulation through inhibition of plasmin-dependent ECM degradation. The aim of… (More)