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1‐Methyl‐3‐propyl‐7‐butylxanthine, a Novel Biochemical Modulator, Enhances Therapeutic Efficacy of Adriamycin
TLDR
1‐Methyl‐3‐propyl‐7‐butylxanthine (XT‐77), which had the greatest inhibitory effect on adriamycin efflux in vitro among the compounds tested, potentiated adriamicin‐induced antitumor activity by causing an increase of adri amycin concentration in the tumor in vitro.