Takayuki Kurazono

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BACKGROUND Enterohemorrhagic Escherichia coli (EHEC) O157:H7 infection causes severe diseases such as bloody diarrhea and hemolytic uremic syndrome (HUS). Although EHEC O157:H7 strains have exhibited high genetic variability, their abilities to cause human diseases have not been fully examined. METHODS Clade typing and stx subtyping of EHEC O157:H7(More)
We developed a method to produce, identify and analyze DNA fragments for the purpose of taxonomic classification. Genome profiling (GP) is a strategy that identifies genomic DNA fragments common to closely related species without prior knowledge of the DNA sequence. Random PCR, one of the key technologies of GP, is used to produce fragments and may be used(More)
Because cholera toxin (CT) is responsible for most of the symptoms induced by Vibrio cholerae infection, detection of CT is critical for diagnosis of the disease. In this study, we constructed an immunochromatographic test strip for detection of CT (CT-IC) with polyclonal antibodies developed against purified recombinant whole CT protein. The detection(More)
identified mainly carbapenem-hydro-lyzing carbapenemase OXA-58 (9). Recently, we showed that the bla NDM-1 gene was carried by a composite transposon bracketed by 2 copies of ISAba125 in A. baumannii (10). Cloning and sequencing of the genetic context of the bla NDM-1 in the first isolate showed that transposon Tn125 was truncated at its 3′-end extremity by(More)
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