Takayuki Fuchigami

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We recently developed a sensitive peripheral analgesic test in mice. Bradykinin, a representative pain-producing substance, when given subcutaneously through a polyethylene tube into the plantar of the limb connected to a transducer, induced a flexor reflex response, in a dose dependent manner. When morphine, a mu-opioid receptor agonist, was added to the(More)
Stir-bar sorptive extraction (SBSE) is a unique method; a sample solution is stirred with a stir bar covered with polydimethylsiloxane. It generally gives clean extract and high recovery rates and is used for analysis of various compounds. In this study, we established a detailed procedure for analysis of 11-nor-9-carboxy-Δ9-tetrahydrocannabinol (THCA), the(More)
Stir bar sorptive extraction is a technique used for extracting target substances from various aqueous matrixes such as environmental water, food, and biological samples. This type of extraction is carried out by rotating a coated stir bar is rotated in the sample solution. In particular, Twister bar is a commercial stir bar that is coated with(More)
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