Takayoshi Tsukahara

Learn More
Resistin, which appears to be related to insulin resistance, is secreted mainly from macrophages in human and some of its polymorphisms have been reported. Based on recent in vitro studies, resistin may be associated with atherosclerosis by mediating endothelial hyperactivity. We investigated whether resistin polymorphism at -420C>G is associated with serum(More)
Sir, Granulocyte colony-stimulating factor (G-CSF) is a hematopoietic growth factor, widely used for the treatment of cytotoxic chemotherapy-induced neutropenia. We report two patients with malignant lymphoma who developed interstitial pneumonitis during or shortly after treatment with G-CSF. Recombinant human GCSF produced by Escherichia coli (Kirin(More)
UNLABELLED Aims/Introduction:  Resistin, an inflammatory cytokine, might be involved in the development of atherosclerosis. In a recent paper, we showed that resistin polymorphism might be a risk marker for stroke susceptibility in Japanese type 2 diabetic patients. We tested whether the serum resistin levels might be also a risk marker of stroke(More)
Rheumatoid arthritis (RA) is a systemic inflammatory disease in which the predominant symptom is polyarthritis that follows a chronic and progressive clinical course characterized by destructive synovitis and various immune disorders. Striking progress in RA treatment was achieved with the emergence of monoclonal antibodies to target cytokines. However,(More)
A 26-year-old man was injured in the traffic accident. He had complicated chest trauma. He came to our hospital by ambulance immediately after rescued from crashed his automobile. He had severe pulmonary contusion with frail chest, pulmonary laceration, tension hemopneumothorax, and hypovolemic shock, and air embolism of the brain. He was managed with(More)
  • 1