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Exocytosis in spermatozoa in response to progesterone and zona pellucida.

• Eduardo R. S. Roldan, Takatoshi Murase, Qi Xian Shi
• Science
• 1994

Exocytosis in mammalian spermatozoa (the acrosome reaction) is a process essential for fertilization. Both progesterone and zona pellucida induce exocytosis in spermatozoa, which may encounter both… (More)

Serum soluble lectin-like oxidized low-density lipoprotein receptor-1 levels are elevated in acute coronary syndrome: a novel marker for early diagnosis.

• Kazutaka Hayashida, Noriaki Kume, +9 authors Toru Kita
• Circulation
• 2005

BACKGROUND Markers of cardiac injury, including troponin-T (TnT), are used to diagnose acute coronary syndrome (ACS); however, markers for plaque instability may be more useful for diagnosing ACS at… (More)

Expression of lectinlike oxidized low-density lipoprotein receptor-1 in human atherosclerotic lesions.

• Hajime Kataoka, Noriaki Kume, +7 authors Toru Kita
• Circulation
• 1999

BACKGROUND Oxidized LDL (Ox-LDL) seems to play key roles in atherogenesis. Lectinlike Ox-LDL receptor-1 (LOX-1) is a recently identified cell-surface receptor for Ox-LDL. The relationship of this… (More)

Inducible expression of lectin-like oxidized LDL receptor-1 in vascular endothelial cells.

• Noriaki Kume, Takatoshi Murase, +4 authors Toru Kita
• Circulation research
• 1998

Endothelial dysfunction, or activation, elicited by oxidized LDL (Ox-LDL) or its lipid constituent, has been implicated in the initiation and progression of atherosclerosis. We have recently… (More)

Polyphosphoinositide-derived diacylglycerol stimulates the hydrolysis of phosphatidylcholine by phospholipase C during exocytosis of the ram sperm acrosome. Effect is not mediated by protein kinase C.

• Eduardo R. S. Roldan, Takatoshi Murase
• The Journal of biological chemistry
• 1994

In ram spermatozoa, treatment with the ionophore A23187 and Ca2+ led to an increase in total diacylglycerol mass and to exocytosis of the acrosomal granule. If sperm cells were prelabeled with… (More)

Progesterone and the zona pellucida activate different transducing pathways in the sequence of events leading to diacylglycerol generation during mouse sperm acrosomal exocytosis.

• Takatoshi Murase, Eduardo R. S. Roldan
• The Biochemical journal
• 1996

We tested the involvement of protein tyrosine kinase and G-protein transducing pathways in the formation of diacylglycerol (DAG) during exocytosis in mouse spermatozoa. In capacitated spermatozoa,… (More)

Inducible expression of LOX-1, a novel receptor for oxidized LDL, in macrophages and vascular smooth muscle cells.

• Noriaki Kume, Hisataka Moriwaki, +5 authors Toru Kita
• Annals of the New York Academy of Sciences
• 2000

Macrophages appear to take up oxidized low density lipoprotein (Ox-LDL) by multiple receptor-mediated pathways. This study, therefore, has been performed to determine if LOX-1, a novel receptor for… (More)

Biosynthesis and post-translational processing of lectin-like oxidized low density lipoprotein receptor-1 (LOX-1). N-linked glycosylation affects cell-surface expression and ligand binding.

• Hajime Kataoka, Noriaki Kume, +6 authors Toru Kita
• The Journal of biological chemistry
• 2000

LOX-1 (lectin-like oxidized low density lipoprotein receptor-1) is a type II membrane protein belonging to the C-type lectin family that can act as a cell-surface receptor for atherogenic oxidized… (More)

Expression of lectin-like oxidized low density lipoprotein receptor-1 in human and murine macrophages: upregulated expression by TNF-alpha.

• Hisataka Moriwaki, Noriaki Kume, +5 authors Toru Kita
• FEBS letters
• 1998

Uptake of oxidized low density lipoprotein (Ox-LDL) and subsequent foam cell transformation have been implicated in early atherogenesis. Although multiple molecules, including class A and B scavenger… (More)

Human recombinant TNF suppresses lipoprotein lipase activity and stimulates lipolysis in 3T3-L1 cells.

• Masanobu Kawakami, Takatoshi Murase, +4 authors Sachio Shibata
• Journal of biochemistry
• 1987

Tumor necrosis factor (TNF) has been reported to be identical to "cachectin," a monokine which we have previously proposed as a mediator of the enhanced catabolism observed in patients or animals… (More)

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