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A serious impediment for seamless roaming between independent wireless LANs (WLANs) is how best to confederate the various WLAN service providers, each having different trust relationships with individuals and each supporting their own authentication schemes which may vary from one provider to the next. We have designed and implemented a comprehensive(More)
E. coli preprotein translocase comprises SecA and SecY/E/G complex. SecA delivers the preprotein to the putative protein-conducting channel formed by SecY/E by undergoing ATP-driven cycles of membrane insertion and deinsertion. SecG renders the translocase highly efficient. An antibody raised against the C-terminal region of SecG inhibits preprotein(More)
We present a multimedia content delivery system that preserves the end-to-end authenticity of original content while allowing content adaptation by intermediaries. Our system utilizes a novel multi-hop signature scheme using Merkle trees that permits selective element removal and insertion. To permit secure element insertion we introduce the notion of a(More)
BACKGROUND The excess and persistent accumulation of fibroblasts due to aberrant tissue repair results in fibrotic diseases such as idiopathic pulmonary fibrosis. Recent reports have revealed significant changes in microRNAs during idiopathic pulmonary fibrosis and evidence in support of a role for microRNAs in myofibroblast differentiation and the(More)
  • Atsushi Sugie, Satoko Hakeda-Suzuki, Emiko Suzuki, Marion Silies, Mai Shimozono, Christoph Möhl +2 others
  • 2015
Neural activity contributes to the regulation of the properties of synapses in sensory systems, allowing for adjustment to a changing environment. Little is known about how synaptic molecular components are regulated to achieve activity-dependent plasticity at central synapses. Here, we found that after prolonged exposure to natural ambient light the(More)
RATIONALE The receptor for advanced glycation end products is a multiligand receptor that plays an important role in regulating the invasiveness and metastatic potential of cancer cells. A recently discovered novel splice variant, the endogenous secretory receptor for advanced glycation end products, mediates the receptor for advanced glycation(More)
Services are capabilities that enable applications and are of crucial importance to pervasive computing in next-generation networks. Service Composition is the construction of complex services from primitive ones; thus enabling rapid and flexible creation of new services. The presence of multiple independent service providers poses new and significant(More)
MT1-MMP is a potent invasion-promoting membrane protease employed by aggressive cancer cells. MT1-MMP localizes preferentially at membrane protrusions called invadopodia where it plays a central role in degradation of the surrounding extracellular matrix (ECM). Previous reports suggested a role for a continuous supply of MT1-MMP in ECM degradation. However,(More)
In 2003, H5N1 avian influenza virus infections were diagnosed in two Hong Kong residents who had visited the Fujian province in mainland China, affording us the opportunity to characterize one of the viral isolates, A/Hong Kong/213/03 (HK213; H5N1). In contrast to H5N1 viruses isolated from humans during the 1997 outbreak in Hong Kong, HK213 retained(More)
During Drosophila visual system development, photoreceptors R7 and R8 project axons to targets in distinct layers of the optic lobe. We show here that the LAR receptor tyrosine phosphatase is required in the eye for correct targeting of R7 axons. In LAR mutants, R7 axons initially project to their correct target layer, but then retract to the R8 target(More)