Takashi Suhara

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A large-scale in vitro study focusing on low-level radiofrequency (RF) fields from mobile radio base stations employing the International Mobile Telecommunication 2000 (IMT-2000) cellular system was conducted to test the hypothesis that modulated RF fields affect malignant transformation or other cellular stress responses. Our group previously reported that(More)
Injectable hydrogels are useful in biomedical applications. We have synthesized hyaluronic acids chemically modified with azide groups (HA-A) and cyclooctyne groups (HA-C), respectively. Aqueous HA-A and HA-C solutions were mixed using a double-barreled syringe to form a hydrogel via strain-promoted [3 + 2] cycloaddition without any catalyst at(More)
Positron emission tomography dynamic study together with compartment model analysis allows the quantification of radioligand binding to receptor sites in the human brain. In the quantitative analysis, parameter estimate error is affected by noise that depends on the collected count, and the reliability of estimated kinetic parameters is important for(More)
Quantification of the receptor binding potential (BP) in human brain has been performed with positron emission tomography. In this quantitative analysis, the uncertainty in estimated kinetic parameters depends on the SNR. Evaluation of the reliability of parameter estimates is important for the optimization of scan protocol and quantitative analysis(More)
S. Saito, K. Sawada, X-Z. Sun, T. Suhara, I. Kanno, and I. Aoki Department of Molecular and Neuroimaging, Graduate School of Medicine, Tohoku University, Sendai, Miyagi, Japan, Laboratory of Anatomy, Department of Physical Therapy, Faculty of Medical and Health Sciences, Japan, Regulation Science Research Group, National Institute of Radiological Sciences,(More)
A large-scale in vitro study focusing on low-level radiofrequency (RF) fields from mobile radio base stations employing the International Mobile Telecommunication 2000 (IMT-2000) cellular system was conducted to test the hypothesis that modulated RF fields induce apoptosis or other cellular stress response that activate p53 or the p53-signaling pathway.(More)
S. Saito, X-Z. Sun, K. Sawada, T. Suhara, I. Kanno, and I. Aoki Department of Molecular and Neuroimaging, Graduate School of Medicine, Tohoku University, Sendai, Miyagi, Japan, Regulation Science Research Group, National Institute of Radiological Sciences, Chiba, Japan, Laboratory of Anatomy, Department of Physical Therapy, Faculty of Medical and Health(More)
Low signal-to-noise ratio (SNR) of time activity curve (TAC) at the voxel level causes severe bias and poor precision for estimated binding potential (BP) in peripheral benzodiazepine receptor (PBR) using nonlinear least square (NLS) fitting. The purpose of this study is to evaluate noise reduction capability of wavelet denoising for estimated BP image. We(More)
Repeated hepatic resections are not uncommon during the surgical management of liver tumors. Postoperative adhesions induced by hepatectomies can have a significant negative impact on subsequent surgeries. We recently developed a new hepatectomy-induced postoperative adhesion animal model to evaluate the anti-adhesion efficacy of commercially available(More)