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We studied the identity and function of the 528-bp gene immediately upstream of Legionella pneumophila F2310 ptsP (enzyme I(Ntr)). This gene, nudA, encoded for a Nudix hydrolase based on the inferred protein sequence. NudA had hydrolytic activity typical of other Nudix hydrolases, such as Escherichia coli YgdP, in that Ap(n)A's, in particular diadenosine… (More)

In portfolio optimization problems, the minimum expected investment risk is not always smaller than the expected minimal investment risk. That is, using a well-known approach from operations research, it is possible to derive a strategy that minimizes the expected investment risk, but this strategy does not always result in the best rate of return on… (More)

The typical behavior of optimal solutions to portfolio optimization problems with absolute deviation and expected shortfall models using replica analysis was pioneeringly estimated by S. Ciliberti et al. [Eur. Phys. B. 57, 175 (2007)]; however, they have not yet developed an approximate derivation method for finding the optimal portfolio with respect to a… (More)

We discuss replica analytic continuation using several simple models in order to prove mathematically the validity of replica analysis, which is used in a wide range of fields related to large scale complex systems. While replica analysis consists of two analytical techniques, the replica trick (or replica analytic continuation) and the thermodynamical… (More)

—Price of anarchy, the performance ratio, which could characterize the loss of efficiency of the distributed supply chain management compared with the integrated supply chain management is discussed by utilizing newsvendor problem in single period which is well-known. In particular, some of remarkable distributed policies are handled, the performance ratios… (More)

Learning behavior of simple perceptrons is analyzed for a teacher-student scenario in which output labels are provided by a teacher network for a set of possibly correlated input patterns, and such that teacher and student networks are of the same type. Our main concern is the effect of statistical correlations among the input patterns on learning… (More)

SUMMARY ∑ Improvement in technology has made it possible to deliver a high dialysis dose in a shorter period of time. Studies of the relationship between dialysis treatment duration and mortality have revealed that the risk of death increased significantly as the treatment time was reduced. The longer duration and increased frequency of dialysis achieve an… (More)

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