Takashi Shinha

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A 54-year-old man with an underlying AIDS experienced fever and lethargy. Magnetic resonance imaging (MRI) showed multiple small ring-enhancement lesions over pons, basal ganglion, thalami, and bilateral cerebral hemisphere. Because of the concurrent pulmonary tuberculosis (TB), presumptive diagnosis of tuberculous meningitis and brain tuberculoma was made.(More)
Clostridium species are anaerobic Gram-positive rods that can cause a broad range of invasive infections in humans, including myonecrosis and bacteremia. Importantly, clostridial bacteremia is frequently associated with underlying medical conditions, such as colonic malignancy. Characterizing Clostridium spp. and understanding their associated clinical(More)
In HIV-infected individuals, macrophages, the key defense effector cells, manifest defective activity in their interactions with a wide variety of opportunistic pathogens, including fungi and protozoa. Understanding the morphological characteristics of intracellular opportunistic pathogens in addition to their pathogenesis is of critical importance to(More)
Mafenide acetate is used in some burn wounds for its ability to penetrate eschar but requires frequent uncomfortable dressing changes for its application. The authors hypothesize that hydrofiber dressings will hold mafenide acetate solution for an extended period of time and maintain antimicrobial activity longer than traditional gauze, thus possibly(More)
Ramsay Hunt syndrome is characterized by varicella zoster virus infection affecting the geniculate ganglion of the facial nerve. It typically presents with vesicles in the external auditory canal associated with auricular pain and peripheral facial nerve paralysis. Although vestibulocochlear nerve is frequently co-involved during the course of Ramsay Hunt(More)
A 37-year-old man with a history of intravenous drug abuse presented with a 1-month history of a fever, chills and fatigue. The presence of a systolic ejection murmur was observed at the apex on a cardiac examination. Transesophageal echocardiography revealed a vegetation measuring 12 mm × 10 mm on the aortic valve. Multiple blood cultures turned positive;(More)
Although acalculous cholecystitis typically occurs in critically ill individuals, it has been described in patients with HIV infection. Recognition of AIDS-related acalculous cholecystitis is important for gastroenterologists to provide optimal therapy, since many different opportunistic pathogens may be involved. Histoplasma capsulatum causes a wide(More)
A 32-year-old man with asthma developed wheezing while swimming in the sea of Florida, USA. The patient was evaluated at a hospital the next day for his unresolved respiratory distress. The patient was hemodynamically stable without signs of anaphylactic shock. On a physical examination, his lungs revealed scattered wheezing, and erythematous papular skin(More)