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- Hiroshi Kobayashi, Yoshihiko Yamada, +9 authors Takashi Kitanaka
- International journal of gynecological cancer…
- 2008
Ovarian cancer is common in women from developed countries. We designed a prospective randomized controlled trial of ovarian cancer screening to establish an improved strategy for the early detection… (More)
- Hiroshi Kobayashi, Kazuhiro Sumimoto, +11 authors Toshihiko Terao
- European journal of obstetrics, gynecology, and…
- 2008
OBJECTIVE
Our prospective studies in Japan have found an increased ovarian cancer incidence in women with ovarian endometrioma (standardized incidence ratio, 8.95; 95% confidence intervals,… (More)
- Tatsuo Yagyu, Yoriko Tsuji, +7 authors Hiroshi Kobayashi
- International journal of gynecological cancer…
- 2006
The purpose of this study was to determine whether Akt and mammalian target of rapamycin (mTOR), downstream targets of phosphatidylinositol 3-kinase, are activated in endometriosis and ovarian cancer… (More)
- Toshiyuki Sado, Katsuhiko Naruse, +6 authors Hiroshi Kobayashi
- Inflammation Research
- 2011
Preeclampsia, a pregnancy-specific hypertensive syndrome, is one of the leading causes of premature births as well as fetal and maternal death. Preeclampsia lacks effective therapies because of the… (More)
- Hiroshi Kobayashi, Ryuji Yoshida, +11 authors Toshihiko Terao
- Experimental dermatology
- 2005
BACKGROUND
Cytokines are produced as a consequence of photo-damaged DNA and oxidative stress in ultraviolet (UV)-exposed keratinocytes. A soybean Kunitz trypsin inhibitor (KTI) down-regulates the… (More)
- Hiroshi Kobayashi, Tatsuo Yagyu, +9 authors Toshihiko Terao
- Cancer research
- 2005
Thalidomide has been used to treat a variety of diseases ranging from alleviation of autoimmune disorders to prevention of metastasis of cancers. It has been shown previously that increased levels of… (More)
- Shoji Tomoda, Tomoko Tamura, Takashi Kitanaka, Sachio Ogita
- American journal of perinatology
- 1996
The purpose of this study is to predict pregnancy-induced hypertension (PIH) by standard methods at the first antenatal visit prior to the 12th gestational week (GW). This is a retrospective study of… (More)
- Taketoshi Noguchi, Toshiyuki Sado, +10 authors Hiroshi Kobayashi
- Mediators of inflammation
- 2010
OBJECTIVE
Individuals with inflammation have a myriad of pregnancy aberrations including increasing their preterm birth risk. Toll-like receptors (TLRs) and receptor for advanced glycation end… (More)
- Shoji Tomoda, Takashi Kitanaka, Sachio Ogita, Atsuo Hidaka
- Asia-Oceania journal of obstetrics and…
- 1994
The purpose of this study is to evaluate an isometric exercise (Hand-Grip test) as a method to predict pregnancy-induced hypertension (PIH). One hundred and twenty-five pregnant women were given the… (More)
- Shozo Yoshida, Akira Onogi, +12 authors Hiroshi Kobayashi
- Journal of clinical ultrasound : JCU
- 2008
The detection of an ovarian mass during pregnancy is often a diagnostic challenge. We describe 2 cases of ovarian endometrioma during pregnancy with marked mural nodules on the cyst wall. The… (More)