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The mollusk shell is a hard tissue consisting of calcium carbonate crystals and an organic matrix. The nacre of the shell is characterized by a stacked compartment structure with a uniformly oriented c axis of aragonite crystals in each compartment. Using a calcium carbonate-binding assay, we identified an acidic matrix protein, Pif, in the pearl oyster(More)
BACKGROUND Preoperative imaging is widely used and extremely helpful in hepatobiliary surgery. However, transfer of preoperative data to a intraoperative situation is very difficult. Surgeons need intraoperative anatomical information using imaging data for safe and precise operation in the field of hepatobiliary surgery. We have developed a new system for(More)
ÐWe describe results obtained from a testbed used to investigate different codings for automatic face recognition. An eigenface coding of shape-free faces using manually located landmarks was more effective than the corresponding coding of correctly shaped faces. Configuration also proved an effective method of recognition, with rankings given to incorrect(More)
STUDY DESIGN The insertional torque of pedicle screws using the cortical bone trajectory (CBT) was measured in vivo. OBJECTIVE To investigate the effectiveness of the CBT technique by measurement of the insertional torque. SUMMARY OF BACKGROUND DATA The CBT follows a mediolateral and caudocephalad directed path, engaging with cortical bone maximally(More)
OBJECTIVE Using 6-[(18)F]fluoro-L-dopa (FDOPA) and [(18)F]fluorodeoxyglucoce (FDG) positron emission tomography (PET), multiple regression analyses were performed to determine the specific brain regions that are related to cognitive and motor symptoms in nondemented patients with Parkinson's disease. METHODS Spatially normalized images of FDOPA influx(More)
Mesenchymal stem cells (MSCs), largely present in the adult human body, represent an attractive tool for the establishment of a stem cell-based therapy for liver diseases. Recently, the therapeutic potential and immunomodulatory activity of MSCs have been revealed. Adipose tissue-derived mesenchymal stem cells (AT-MSCs), so-called adipose-derived stem cells(More)
BACKGROUND To examine the effect of multicomponent exercise program on memory function in older adults with mild cognitive impairment (MCI), and identify biomarkers associated with improvement of cognitive functions. METHODOLOGY/PRINCIPAL FINDINGS Subjects were 100 older adults (mean age, 75 years) with MCI. The subjects were classified to an amnestic MCI(More)
BACKGROUND AND AIM Multipotential mesenchymal stem cells (MSC), present in many organs and tissues, represent an attractive tool for the establishment of a successful stem cell-based therapy in the field of regeneration medicine. Adipose tissue mesenchymal stem cells (AT-MSC), known as adipose-derived stem cells (ASC) are especially attractive in the(More)
Silencing gene expression by siRNAs is rapidly becoming a powerful tool for the genetic analysis of mammalian cells. However, the rapid degradation of siRNA and the limited duration of its action call for an efficient delivery technology. Accordingly, we describe here that Atelocollagen complexed with siRNA is resistant to nucleases and is efficiently(More)
OBJECTIVE In this study, we determined the possible usefulness of sentinel node (SN) mapping guided by indocyanine green (ICG) fluorescence imaging in the management of gastric cancer. SUMMARY BACKGROUND DATA ICG fluorescence imaging system has recently been developed for obtaining biochemical information from living tissues. METHODS Our series(More)