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We propose a method for extracting semantic orientations of words: desirable or undesirable. Regarding semantic ori-entations as spins of electrons, we use the mean field approximation to compute the approximate probability function of the system instead of the intractable actual probability function. We also propose a criterion for parameter selection on(More)
Prostaglandin (PG) D2 is well known as a mediator of inflammation. Hematopoietic PGD synthase (HPGDS) is responsible for the production of PGD2 involved in inflammatory responses. Microglial activation and astrogliosis are commonly observed during neuroinflammation, including that which occurs during demyelination. Using the genetic demyelination mouse(More)
In this paper, we deal with automatic knowledge acquisition from text, specifically the acquisition of <i>causal relations</i>. A causal relation is the relation existing between two events such that one event causes (or enables) the other event, such as &#8220;hard rain causes flooding&#8221; or &#8220;taking a train requires buying a ticket.&#8221; In(More)
Cortical spreading depression is an excitatory wave of depolarization spreading throughout cerebral cortex at a rate of 2-5 mm/min and has been implicated in various neurological disorders, such as epilepsy, migraine aura, and trauma. Although sleepiness or sleep is often induced by these neurological disorders, the cellular and molecular mechanism has(More)
We propose a method for extracting semantic orientations of phrases (pairs of an adjective and a noun): positive, negative, or neutral. Given an adjective, the semantic orientation classification of phrases can be reduced to the classification of words. We construct a lexical network by connecting similar/related words. In the network , each node has one of(More)
We propose models for semantic orienta-tions of phrases as well as classification methods based on the models. Although each phrase consists of multiple words, the semantic orientation of the phrase is not a mere sum of the orientations of the component words. Some words can invert the orientation. In order to capture the property of such phrases, we(More)
Paraquat is a widely used herbicide that is structurally similar to the known dopaminergic neurotoxicant 1-methyl-4-phenyl-pyridine and acts as a potential etiologic factor for the development of Parkinson's disease. In this study, we investigated the protective roles of lipocalin-type prostaglandin (PG) D synthase (L-PGDS) against paraquat-mediated(More)
This paper reports the results of our ongoing research into the automatic acquisition of causal knowledge. We created a new typol-ogy for expressing the causal relations — cause, effect, precond(ition) and means — based mainly on the volitionality of the related events. From our experiments using the Japanese resultative connective " tame " , we achieved(More)
Members of the genus Trypanosoma cause African trypanosomiasis in humans and animals in Africa. Infection of mammals by African trypanosomes is characterized by an upregulation of prostaglandin (PG) production in the plasma and cerebrospinal fluid. These metabolites of arachidonic acid (AA) may, in part, be responsible for symptoms such as fever, headache,(More)
We investigated of the characteristics of in-text causal relations. We designed causal relation tags. With our designed tag set, three annotators annotated 750 Japanese newspaper articles. Then, using the annotated corpus, we investigated the causal relation instances from some viewpoints. Our quantitative study shows that what amount of causal relation(More)