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Trends in smoking and lung cancer mortality in Japan, by birth cohort, 1949-2010.
OBJECTIVE To determine smoking trends in Japan in comparison with lung cancer mortality. METHODS Age-specific smoking prevalence among cohorts born between 1897 and 1985 were determined for theExpand
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An autoregressive linear mixed effects model for the analysis of longitudinal data which show profiles approaching asymptotes.
In longitudinal data, a continuous response sometimes shows a profile approaching an asymptote. For such data, we propose a new class of models, autoregressive linear mixed effects models in whichExpand
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Changes in body mass index by birth cohort in Japanese adults: results from the National Nutrition Survey of Japan 1956–2005
Background The National Nutrition Survey, Japan (NNS-J) provides annual anthropometric information for a whole nation over 50 years. Based on this survey, the mean body mass index (BMI) of JapaneseExpand
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Do overweight children necessarily make overweight adults? Repeated cross sectional annual nationwide survey of Japanese girls and women over nearly six decades
Objective To compare growth curves of body mass index from children to adolescents, and then to young adults, in Japanese girls and women in birth cohorts born from 1930 to 1999. Design RetrospectiveExpand
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Analysis of covariance with pre-treatment measurements in randomized trials under the cases that covariances and post-treatment variances differ between groups.
When primary endpoints of randomized trials are continuous variables, the analysis of covariance (ANCOVA) with pre-treatment measurements as a covariate is often used to compare two treatment groups.Expand
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Dose-response relationship from longitudinal data with response-dependent dose modification using likelihood methods.
In some clinical trials or clinical practice, the therapeutic agent is administered repeatedly, and doses are adjusted in each patient based on repeatedly measured continuous responses, to maintainExpand
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Analysis of covariance with pre-treatment measurements in randomized trials: comparison of equal and unequal slopes.
In randomized trials, an analysis of covariance (ANCOVA) is often used to analyze post-treatment measurements with pre-treatment measurements as a covariate to compare two treatment groups. RandomExpand
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Impacts of early smoking initiation: long-term trends of lung cancer mortality and smoking initiation from repeated cross-sectional surveys in Great Britain
Objective To show long-term trends of smoking initiation in Great Britain including unanalysed data and assess the impact of early smoking initiation on the lung cancer mortality in later agesExpand
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A double-blind randomized study assessing safety and efficacy following one-year adjunctive treatment with bitopertin, a glycine reuptake inhibitor, in Japanese patients with schizophrenia
BackgroundBitopertin, a glycine reuptake inhibitor, was investigated as a novel treatment for schizophrenia. We report all the results of a double-blind randomized study assessing safety and efficacyExpand
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An autoregressive linear mixed effects model for the analysis of longitudinal data which include dropouts and show profiles approaching asymptotes.
We are interested in longitudinal data of a continuous response that show profiles with an initial sharp change and approaching asymptotes for each patient, and many patients drop out with a reasonExpand
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