Takao Hanada

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The mammalian mitochondrial (mt) ribosome (mitoribosome) is a bacterial-type ribosome but has a highly protein-rich composition. Almost half of the rRNA contained in the bacterial ribosome is replaced with proteins in the mitoribosome. Escherichia coli elongation factor G (EF-G Ec) has no translocase activity on the mitoribosome but EF-G mt is functional on(More)
All medically useful antibiotics should have the potential to distinguish between target microbes (bacteria) and host cells. Although many antibiotics that target bacterial protein synthesis show little effect on the translation machinery of the eukaryotic cytoplasm, it is unclear whether these antibiotics target or not the mitochondrial translation(More)
Author(s) Kawakami, Hiroshi; Maguchi, Hiroyuki; Mukai, Tsuyoshi; Hayashi, Tsuyoshi; Sasaki, Tamito; Isayama, Hiroyuki; Nakai, Yousuke; Yasuda, Ichiro; Irisawa, Atsushi; Niido, Teitetsu; Okabe, Yoshinobu; Ryozawa, Shomei; Itoi, Takao; Hanada, Keiji; Kikuyama, Masataka; Arisaka, Yoshifumi; Kikuchi, Shogo Citation Gastrointestinal Endoscopy, 75(2): 362-372(More)
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