Takanori Aonuma

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Poststroke patients with functional constipation, assessed by the Rome III criteria, from 6 hospitals were recruited in a study on the effects of the traditional Japanese medicine Daikenchuto (DKT) on constipation. Thirty-four patients (17 men and 17 women; mean age: 78.1 ± 11.6 years) were randomly assigned to 2 groups; all patients received conventional(More)
The rat model of N-methyl-N-nitrosourea (MNU)-induced colorectal carcinogenesis was studied to determine histogenesis and evaluate early proliferative lesions and invasive carcinoma by the measurement of DNA content. Twenty-five male Fischer rats, weighing 150-160 g, were intra-rectally given MNU dissolved in distilled water, at a dose of 2 mg/rat, 3 times(More)
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