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  • T. Hase, P. L. Summers, K. H. Eckels
  • 1989
The entry modes of Japanese encephalitis (JE) and dengue-2 (DEN-2) viruses into C6/36 mosquito cells and of DEN-2 virus into human peripheral blood monocytes in vitro were studied. Inoculation of either JE or DEN-2 virions into C6/36 cells resulted in direct penetration of the virions into the cytoplasm at the cell surface in 3 stages. At stage 1, virions(More)
  • T. Hase, P. L. Summers, W. Houston Cohen
  • 1989
The entry modes of Semliki Forest virus and Japanese encephalitis virus into C6/36 cells were compared by electron microscopic observation. At physiological pH, the two viruses showed characteristically different entry modes. Following attachment to the plasma membrane, many SF virions appeared within plasma membrane invaginations and cytoplasmic vesicles;(More)
  • T. Hase, P. L. Summers, K. H. Eckels, W. B. Baze
  • 1987
The maturation process of dengue-2 virus in C6/36 mosquito cells was studied by electron microscopy at 12, 16, 24, 48, and 78 hours postinoculation (p.i.) and by immunoelectron microscopy at 48 and 78 hours p.i. Maturing virions appeared within cytoplasmic vacuoles and on the surface of infected cells from 24 hours p.i. onward in close topographical(More)
  • T. Hase, P. L. Summers, K. H. Eckels, W. B. Baze
  • 1987
The maturation process of Japanese encephalitis (JE) virus in C6/36 cells in vitro and in mouse brain cells in vivo was studied by electron microscopy. In the C6/36 cell infection, 500 to 2250 virions per cell were released into the medium during the period of study; yet, no virus budding process was observed at the host cell membranes. JE virions at(More)
  • T. Hase, D. R. Dubois, P. L. Summers, M. B. Downs, M. A. Ussery
  • 1993
The replication rates and pathogenicities of the SA 14 parent and SA 14-14-2 vaccine strains of Japanese encephalitis (JE) virus in neurons of the mouse brain following intracerebral inoculation were compared. All the mice inoculated with the SA 14 parent strain died within one week postinoculation (p.i.), whereas all the mice inoculated with the SA 14-14-2(More)
In this paper, a new desktop NC machine tool with compliance controllability is presented for finishing metallic molds with small curved surface. The NC machine tool consists of three single-axis robots with high position resolution. A tool attached to the tip of the z-axis has a small ball-end shape. Also, the control system of the NC machine tool is(More)
For the researches of biped walking robot, energy-efficiency is an important issue. We have proposed an optimal trajectory planning method based on a function approximation method, and applied it for 2D biped walking model. With this method, we obtained the solution of minimal square integration value of the input torque. Before that, this method only(More)
In order to implement walking efficiency and environmental adapting ability to a biped locomotion, it is required to combine passive dynamic walking and active one. In this paper, a passive/active unified dynamic walking for biped locomotion was proposed. Firstly, a passive/active unified actuator that has a torque detector and is actively controlled by(More)
For the researches of biped walking robot, energy-efficiency is an important issue. We have proposed an optimal trajectory planning method based on a function approximation method, and applied it for 2D biped walking model. With the method, we obtained the solution of minimal square integration value of the input torque. Before that, this method only(More)
  • Y. Hata, T. Hase, +7 authors K. Inoue
  • 2006
Pediatric liver transplantation has become increasingly successful, but donor scarcity is a major limitation. We studied fetal liver-cell transplantation as an alternative to provide functional hepatic replacement and evaluated the efficacy of the intraperitoneal (i.p.) transplantation of fetal liver cells in the treatment of acute hepatic failure in rats.(More)