Takahiro Takimoto

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Distribution of cerebellothalamic neurons projecting to the ventral nuclei of the thalamus was examined in the cat, using the horseradish peroxidase (HRP) method. After injections of HRP within the lateral or ventrolateral portions of the ventro-anterior and ventrolateral nuclear complex of the thalamus (VA-VL), neurons labeled retrogradely with HRP were(More)
The cervical dorsal root ganglia (C5-C8) of the cat were examined in vivo with an electron microscope. Cell processes of unknown origin were observed to invade the area between the satellite cell sheaths and the ganglion cells, and their terminals were found to be in synaptic contact with the soma of the ganglion cells. Like chemical synapses, these(More)
Dorsal root ganglia (C3) of the cats have been examined with the electron microscope after dorsal and ventral rhizotomies and horseradish peroxidase injection into the ventral horn of the spinal cord (C3). Axo-somatic synapses were found in the dorsal root ganglia and, moreover, they showed early signs of anterograde terminal degeneration after a 48 h(More)
We analyzed genetic variants of the promoter region of the cholecystokinin (CCK; which modulates the release of dopamine) gene, and intron 1 and exon 5 of the CCKA receptor gene, and performed association analyses of nicotine dependence using an allele-specific amplification (ASA) method and PCR-RFLP methods. There was a significant difference between the(More)
The relationship between nicotine metabolism of CYP2A6 and the smoking behavior in a Japanese population was investigated. The CYP2A6 genotypes were determined by the PCR method. There was a significant difference in the frequency of the CYP2A6AST;4C allele, which is a whole deleted allele for the human CYP2A6 gene, between smokers and nonsmokers. The(More)
In the past, there have been many epidemiological and genetic studies of mood disorders, schizophrenia, and alcohol dependence, and in this study, the human serotonin 2A receptor (5-HTR2A) polymorphism was examined in 80 patients with mood disorders, 50 patients with schizophrenia and 41 patients with alcohol dependence. 5-HTR is related to affectivity,(More)
Panic disorder (PD) is the repeated sudden occurrence of panic attacks, episodes characterized by psychological symptoms. Peripheral benzodiazepine receptor (PBR) is closely associated with personality traits for anxiety tolerance, and that it holds promise as a biological marker of stressful conditions. We have performed association analyses using the(More)
Focal segmental glomerular hyalinosis and/or sclerosis (FSHS) was observed in five Wistar-Imamichi rats with congenital unilateral hydronephrosis (CUH rats). Marked proteinuria (164.9 +/- 138.4 mg/day) was observed in the CUH rats. Immunoperoxidase staining for IgM, C3 and IgG was positive in the glomeruli, showing in a focal, segmental pattern that(More)
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