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—This paper presents a 60-GHz direct-conversion RF front-end and baseband transceiver including analog and digital circuitry for PHY functions. The 65-nm CMOS front-end consumes 319 and 223 mW in transmitting and receiving mode, respectively. It is capable of more than 7-Gb/s 16QAM wireless communication for every channel of the 60-GHz standards, which can(More)
Ghrelin, an endogenous ligand for the GH secretagogue receptor, is a hormone expressed in stomach and other tissues, such as hypothalamus, testis, and placenta. This hormone acts at a central level to stimulate GH secretion and food intake. Little is known, however, about the molecular forms and physiological roles of ghrelin within the hypothalamus. In(More)
Neuromedin U (NMU) is a neuropeptide that is expressed in the gastrointestinal tract and central nervous system. NMU interacts with two G protein-coupled receptors, NMU-R1 and NMU-R2. Whereas NMU-R2 localizes predominantly to nerve cells, NMU-R1 is expressed in peripheral tissues including lymphocytes and monocytes, suggesting a role of NMU in(More)
Ghrelin, first identified in the stomach, is a ligand of an orphan G-protein coupled receptor. Early studies indicated that the growth hormone secretagogue receptor (GHS-R; ghrelin receptor) is ubiquitously distributed in the brain. In addition, centrally administered ghrelin and ghrelin receptor agonist have effects on central neurons in many regions,(More)
  • Takahiro Sato, Thai H. Tran, Amy R. Peck, Melanie A. Girondo, Chengbao Liu, Chelain R. Goodman +9 others
  • 2014
Prolactin controls the development and function of milk-producing breast epithelia but also supports growth and differentiation of breast cancer, especially luminal subtypes. A principal signaling mediator of prolactin, Stat5, promotes cellular differentiation of breast cancer cells in vitro, and loss of active Stat5 in tumors is associated with(More)