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Transcription of messenger RNAs (mRNAs) for Notch signaling molecules oscillates with 2-hour cycles, and this oscillation is important for coordinated somite segmentation. However, the molecular mechanism of such oscillation remains to be determined. Here, we show that serum treatment of cultured cells induces cyclic expression of both mRNA and protein of… (More)

We cull collisions between very large numbers of moving bodies using graphics processing units (GPUs). To perform massively parallel sweep-and-prune (SaP), we mitigate the great density of intervals along the axis of sweep by using principal component analysis to choose the best sweep direction, together with spatial subdivisions to further reduce the… (More)

Analyses of energy metabolism in human cancer have been difficult because of rapid turnover of the metabolites and difficulties in reducing time for collecting clinical samples under surgical procedures. Utilization of xenograft transplantation of human-derived colon cancer HCT116 cells in spleens of superimmunodeficient NOD/SCID/IL-2Rγ(null) (NOG) mice led… (More)

We present a sliced data structure that is effective for use in neighboring particle search for particle-based simulations. In this method, a grid is dynamically constructed to fit to a particle distribution. Rather than computing the grid to fit perfectly to the particle distribution, it compute a grid with some margin to the distribution. This lowers the… (More)

A theory for obtaining a waveform for the effective entrainment of a weakly forced oscillator is presented. Phase model analysis is combined with calculus of variation to derive a waveform with which entrainment of an oscillator is achieved with a minimum power forcing signal. Optimal waveforms are calculated from the phase response curve and a solution to… (More)

The appearance of hair plays a critical role in synthesizing realistic looking human characters. However, due to the high complexity in hair geometry and the scattering nature of hair fibers, rendering hair with photorealistic quality and at interactive speeds remains as an open problem in computer graphics. Previous approaches attempt to simplify the… (More)

In this paper, we propose an improved computation model of wall boundary in Smoothed Particle Hydrodynamics, a particle method for fluid simulation. Generally, particle methods calculate a wall boundary by converting it to wall particles. The proposed method uses a distance function calculated from a polygon model as a wall boundary. As a result, fluid… (More)

We propose a sketch-based system to design volume data from scratch. The user splits a surface model and paints brush strokes to volumetrically fill the 3D space. We extend exisiting sketch-based modeling systems in various ways. First, we use the cross-sectional plane as the interface to design internal structures. Second, the predefined surface geometries… (More)

As physical laws govern the motion of objects around us, a physically-based simulation plays an important role in computer graphics. For instance, the motion of a fluid, which is difficult to generate by hand, can be produced by solving the governing equations. Acceleration of a simulation is one of the most important research themes because the speed and… (More)