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We show that the mouse macrophage-restricted F4/80 protein is not required for the development and distribution of tissue macrophages but is involved in the generation of antigen-specific efferent regulatory T (T reg) cells that suppress antigen-specific immunity. In the in vivo anterior chamber (a.c.)-associated immune deviation (ACAID) model of peripheral(More)
In this paper, a wearable walking support system for people who have difficulties in walking because of weakened lower extremities is proposed. We propose a model-based control algorithm for the wearable device without using biological signals, that is, the knee joint support moment is calculated as a function of the user’s posture and the GRF based(More)
In a model of peripheral tolerance called anterior chamber-associated immune deviation (ACAID), the differentiation of the T regulatory cells depends on NKT cells and occurs in the spleen. In this study, we show that NKT cells that express the invariant (i) TCR and are the CD1d-reactive NKT cells (required for development of peripheral tolerance) actually(More)
Following inoculation of Ag into the anterior chamber (a.c.), systemic tolerance develops that is mediated in part by Ag-specific efferent CD8(+) T regulatory (Tr) cells. This model of tolerance is called a.c.-associated immune deviation. The generation of the efferent CD8(+) Tr cell in a.c.-associated immune deviation is dependent on IL-10-producing,(More)
— In this paper, to support antigravity muscles during stance phase more strongly, we propose a new wearable antigravity muscles support system, which supports antigravity muscles around the knee and hip joint. In this system, a posture-based control algorithm for the device without using biological signals is implemented to the wearable antigravity muscles(More)
—This paper considers bifurcation phenomena in a simplified hysteresis neural network. The network consists of three cells and has three control parameters. We have discovered that the simple system exhibits various attractors: stable equilibria, periodic orbits, and chaos. Since the system is piecewise linear, the return map and Lyapunov exponents are(More)
In this paper, to construct the system, which can assist daily activities of physically weak person more smartly, we propose a new wearable antigravity muscles support system, which supports antigravity muscles based on the posture and motion of user. In this system, a dynamics-based control algorithm for the device without using biological signals is(More)
We have developed a wearable anti-gravity muscle support system, which assists daily activities of physically weak persons by reducing the load to lower extremities. Many activities of human beings are performed smartly by cooperative motions of different body parts to distribute loads. In this paper, we propose a dynamics-based support concept adapted to(More)