Learn More
Membranes allow the compartmentalization of biochemical processes and are therefore fundamental to life. The conservation of the cellular membrane, combined with its accessibility to secreted proteins, has made it a common target of factors mediating antagonistic interactions between diverse organisms. Here we report the discovery of a diverse superfamily(More)
BACKGROUND The type VI secretion system (T6SS) has emerged as a protein secretion system important to several gram-negative bacterial species. One of the common components of the system is Hcp, initially described as a hemolysin co-regulated protein in a serotype O17 strain of Vibrio cholerae. Homologs to V. cholerae hcp genes have been found in all(More)
We identified and characterized the iron-binding protein Dps from Campylobacter jejuni. Electron microscopic analysis of this protein revealed a spherical structure of 8.5 nm in diameter, with an electron-dense core similar to those of other proteins of the Dps (DNA-binding protein from starved cells) family. Cloning and sequencing of the Dps-encoding gene(More)
In large classes, teachers find it difficult to care about the personality and ability of individual students. One of the ways to grasp the learning state of students is to conduct a number of short tests during every class. If a system can automatically give the appropriate instructions and teaching materials to individual students based on the test(More)
Many Gram-negative bacteria rely on a type VI secretion system (T6SS) to infect eukaryotic cells or to compete against other microbes. Common to these systems is the presence of two conserved proteins, in Vibrio cholerae denoted VipA and VipB, which have been shown to interact in many clinically relevant pathogens. In this study, mutagenesis of a defined(More)
In this paper, we propose the concept of a "mobile microscope". This is a hand-held microscope that can be used for observation in various places. Because microscopes which have a small observable area and are vulnerable to vibrations, images from hand-held microscopes are usually blurred. We propose a method of stabilizing images from a microscope which(More)
We propose a concept of " mobile microscope " for handheld use, which enable various places to be observable. We propose an image stabilization method for images from microscope effected by handshake. This method is based on high-speed visual feedback with an inclined image sensor to measure the 3D movements of a microscope. We developed a trial microscope(More)
We propose a novel automatic tracking system capable of tracking fast-moving, small objects under extreme conditions by using high-speed visual feedback for assessing sperm chemotaxis. The system shows remarkable performance and versatility, good enough for practical use in biology. Experimental results showed that we successfully achieved continuous stable(More)