Takaharu Ishibashi

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Inadequate nutrition complicates the clinical course of critically ill patients, and many of these patients develop pulmonary edema. However, little is known about the effect of malnutrition on the mechanisms that resolve alveolar edema. Therefore, we studied the mechanisms responsible for the decrease in alveolar fluid clearance in rats exposed to(More)
Wide-bandgap semiconductors such as silicon carbide (SiC) and gallium nitride (GaN) are promising materials for next-generation power devices. We have fabricated a normally on GaN-based high-electron-mobility transistor (GaN HEMT) for power electronic converters. In this paper, the current collapse phenomena, which are distinctive characteristics of GaN(More)
Differential taste responsiveness and functional role of the two taste nerves, the chorda tympani (CT) and the glossopharyngeal (GL), were studied in mice by examining neural and behavioral responses to an essential amino acid, L-lysine (Lys). Relative responses to Lys were larger in the GL than in the CT nerve. The neural threshold for the Lys response was(More)
Release of glutamate during inflammation and injury changes sensitivity and transmission efficiency of noxious sensory information via glutamate receptors. We found that activation of metabotropic glutamate receptor type 5 (mGluR5) transiently increased, and then subsequently decreased, noxious heat sensitivity. Similarly, mGluR5 activation in cultured(More)
Damaged tissues release glutamate and other chemical mediators for several hours. These chemical mediators contribute to modulation of pruritus and pain. Herein, we investigated the effects of long-term activation of excitatory glutamate receptors on functional expression of transient receptor potential vaniloid type 1 (TRPV1) in dorsal root ganglion (DRG)(More)
Dear Sir, I would like to address the earlier Letter to the Editor 'The pathophysiological significance of red blood cell nitric oxide concentrations in inflammatory Behçet's disease' by Everklioglu et al. in Mediators of Inflammation . 1 It is not hard to accept that NO production is enhanced in active inflammation in Behçet's disease, and this may be(More)
Using an isolated perfused rat heart preparation, the protective effects of lidocaine and diltiazem on ischemic derangements of myocardial energy metabolism were studied with 31P-nuclear magnetic resonance spectroscopy. The hearts were perfused with a solution containing lidocaine (4.27 x 10(-5), 12.80 x 10(-5) M) or diltiazem (2.22 x 10(-7), 2.22 x 10(-6)(More)
Studies on the marginal zone and colloid of the pituitary cleft in pituitaries of rats aged 2 to 88 days were performed by light and electron microscopy. From 10 days of age the intermediate lobe could be divided into two parts, i.e., the marginal layer and the intermediate lobe proper. The former part consisted of agranular cells facing the cleft; the(More)
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