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  • Soroku Ichihara, Takaaki Senbonmatsu, Edward Price, Tomoko Ichiki, F. Andrew Gaffney, Tadashi Inagami
  • Medicine
  • Circulation
  • 2001 (First Publication: 17 July 2001)
  • BACKGROUND The roles of angiotensin II (Ang II) in the regulation of heart function under normal and pathological conditions have been well documented. Although 2 types of Ang II receptor (AT(1) andContinue Reading
  • Takaaki Senbonmatsu, Soroku Ichihara, Edward Price, F. Andrew Gaffney, Tadashi Inagami
  • Medicine
  • The Journal of clinical investigation
  • 2000 (First Publication: 1 August 2000)
  • The pathophysiological roles of the angiotensin II type 2 receptor (AT(2)) in cardiac hypertrophy remain unclear. By the targeted deletion of mouse AT(2) we were able to prevent the left ventricularContinue Reading
  • Jean-Sébastien Silvestre, Radia Tamarat, +7 authors Bernard I Lévy
  • Biology, Medicine
  • Circulation research
  • 2002 (First Publication: 31 May 2002)
  • This study examined the potential role of angiotensin type 2 (AT(2)) receptor on angiogenesis in a model of surgically induced hindlimb ischemia. Ischemia was produced by femoral artery ligature inContinue Reading
  • Yasumori Sujino, Jun Tanno, +4 authors Shigeyuki Nishimura
  • Medicine
  • Journal of cardiology
  • 2015 (First Publication: 1 September 2015)
  • BACKGROUND The optimal treatment strategies for acute ST-elevation myocardial infarction (STEMI) in older patients are unclear because of the high risk of mortality in this population.Continue Reading
  • Ning Wang, Zhe Li, +5 authors Zhizhuang Joe Zhao
  • Biology, Medicine
  • Journal of Biological Chemistry
  • 2006 (First Publication: 4 August 2006)
  • SHP-1 and SHP-2 are two Src homology 2 domain-containing tyrosine phosphatases with major pathological implications in cell growth regulating signaling. They share significant overall sequenceContinue Reading
  • Jun Tanno, Shintaro Nakano, +4 authors Shigeyuki Nishimura
  • Medicine
  • PloS one
  • 2015 (First Publication: 21 January 2015)
  • Background and Aims The degree of coronary artery stenosis should be assessed both anatomically and functionally. We observed that the intensity of blood speckle (IBS) on intravascular ultrasoundContinue Reading
  • Shintaro Nakano, Masahiro Takahashi, +7 authors Shigeyuki Nishimura
  • Medicine
  • Cardiology journal
  • 2016 (First Publication: 30 June 2016)
  • BACKGROUND Trastuzumab, used to treat breast cancer overexpressing human epidermal growth factor receptor 2, may be cardiotoxic. Cardiac magnetic resonance (CMR) imaging with myocardial strainContinue Reading