Tailoi Chan-Ling

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Development of retinal vasculature is mediated by hypoxia-induced vascular endothelial growth factor (VEGF) expression by neuroglia.

Jonathan R. Stone, Ahuva Itin, +4 authors E. Keshet
The Journal of neuroscience : the official…
1995

We have studied the role of the hypoxia-inducible angiogenic growth factor vascular endothelial growth factor (VEGF) in the induction and control of vessel growth in the developing retina of rats and… (More)

Vascularization of the human fetal retina: roles of vasculogenesis and angiogenesis.

Steven Hughes, Haidong Yang, Tailoi Chan-Ling
Investigative ophthalmology & visual science
2000

PURPOSE To characterize the topography of and the cellular processes that underlie vascularization of the human retina. METHODS The vasculature of human eyes obtained from fetuses ranging in age… (More)

Nady Braidy, Gilles J Guillemin, Hussein Mansour, Tailoi Chan-Ling, Anne Poljak, Ross Grant
PloS one
2011

The cofactor nicotinamide adenine dinucleotide (NAD+) has emerged as a key regulator of metabolism, stress resistance and longevity. Apart from its role as an important redox carrier, NAD+ also… (More)

Characterization of smooth muscle cell and pericyte differentiation in the rat retina in vivo.

Suzanne Hughes, Tailoi Chan-Ling
Investigative ophthalmology & visual science
2004

PURPOSE To identify and apply a range of suitable mural cell markers and undertake an in vivo characterization of pericyte and smooth muscle cell (SMC) differentiation in the developing rat retina.… (More)

Differentiation and migration of astrocyte precursor cells and astrocytes in human fetal retina: relevance to optic nerve coloboma.

Yi Wei Chu, Steven Hughes, Tailoi Chan-Ling
FASEB journal : official publication of the…
2001

The presence of astrocyte precursor cells (APCs) and time course and topography of astrocyte differentiation during development were investigated by triple-label immunohistochemistry with intact… (More)

Perforin mediated apoptosis of cerebral microvascular endothelial cells during experimental cerebral malaria.

Sarah M. Potter, Tailoi Chan-Ling, +4 authors Nicholas Henry Hunt
International journal for parasitology
2006

Cerebral malaria is a serious complication of Plasmodium falciparum infection. We have investigated the role of perforin in the pathogenesis of cerebral malaria in a murine model (Plasmodium berghei… (More)

Glial, vascular, and neuronal cytogenesis in whole-mounted cat retina.

Tailoi Chan-Ling
Microscopy research and technique
1997

A method was developed for detecting cytogenesis in retinal whole-mount preparations by bromodeoxyuridine (BrdU) immunohistochemistry. Because BrdU is a nonspecific marker that labels all cells in… (More)

Divalent metal transporter 1 (DMT1) regulation by Ndfip1 prevents metal toxicity in human neurons.

J Howitt, Ulrich Putz, +8 authors Senyue Zhang andWenan Tan
Proceedings of the National Academy of Sciences…
2009

The regulation of metal ion transport within neurons is critical for normal brain function. Of particular importance is the regulation of redox metals such as iron (Fe), where excess levels can… (More)

Degeneration of astrocytes in feline retinopathy of prematurity causes failure of the blood-retinal barrier.

Tailoi Chan-Ling, Jonathan R. Stone
Investigative ophthalmology & visual science
1992

This study addresses the role of astrocytes in the genesis of retinopathy of prematurity, examined in the feline model of this condition. Evidence is presented that the hypoxia of retinopathy of… (More)

Development of retinal vasculature in the cat: processes and mechanisms.

Tailoi Chan-Ling, Péter Halász, Jonathan R. Stone
Current eye research
1990

Two principal processes can be distinguished in the development of the retinal circulation in the cat. One process, which forms most of the inner layer of vasculature, involves three stages. First,… (More)

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