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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
In 2008 we published the first set of guidelines for standardizing research in autophagy. Since then, research on this topic has continued to accelerate, and many new scientists have entered theExpand
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ATG8 lipidation and ATG8-mediated autophagy in Arabidopsis require ATG12 expressed from the differentially controlled ATG12A AND ATG12B loci.
Autophagic recycling of intracellular plant constituents is maintained at a basal level under normal growth conditions but can be induced in response to nutritional demand, biotic stress, andExpand
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The ATG1/ATG13 Protein Kinase Complex Is Both a Regulator and a Target of Autophagic Recycling in Arabidopsis[C][W]
This work demonstrates that an ATG1/13 kinase complex analogous to such complexes regulating autophagy in yeast and metazoans exists in Arabidopsis. The ATG1/13 complex is central to autophagicExpand
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Autophagic Recycling Plays a Central Role in Maize Nitrogen Remobilization
Characterization of maize autophagy through detailed transcriptome studies and phenotypic and 15N-partitioning analyses of atg12 mutants reveal a central role for autophagy in nitrogenExpand
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AUTOPHAGY-RELATED11 Plays a Critical Role in General Autophagy- and Senescence-Induced Mitophagy in Arabidopsis[W]
The ATG1/13 kinase complex that regulates autophagy also includes ATG11 and ATG101, with ATG11 helping regulate the phosphorylation and turnover of ATG1 and ATG13, tether the complex to developingExpand
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The ATG Autophagic Conjugation System in Maize: ATG Transcripts and Abundance of the ATG8-Lipid Adduct Are Regulated by Development and Nutrient Availability1[W][OA]
Plants employ sophisticated mechanisms to recycle intracellular constituents needed for growth, development, and survival under nutrient-limiting conditions. Autophagy is one important route in whichExpand
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Genetic analysis of opaque2 modifier loci in quality protein maize
Quality protein maize (QPM) was created by selecting genetic modifiers that convert the starchy endosperm of an opaque2 (o2) mutant to a hard, vitreous phenotype. Genetic analysis has shown thatExpand
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Delivery of Prolamins to the Protein Storage Vacuole in Maize Aleurone Cells[W]
This study uses a combination of molecular approaches, in vivo imaging of fluorescent proteins, and structural analysis by electron tomography to study the synthesis and transport of storage proteinsExpand
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Autophagy-Related Proteins Are Required for Degradation of Peroxisomes in Arabidopsis Hypocotyls during Seedling Growth[C][W]
This work reveals a function for autophagy in Arabidopsis hypocotyls after germination. By delivering peroxisomes and other cytoplasmic components to the lytic vacuole for degradation, autophagicExpand
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A Revised Assay for Monitoring Autophagic Flux in Arabidopsis thaliana Reveals Involvement of AUTOPHAGY-RELATED9 in Autophagy
Autophagy targets cytoplasmic cargo to a lytic compartment for degradation. Autophagy-related (Atg) proteins, including the transmembrane protein Atg9, are involved in different steps of autophagy inExpand
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