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This paper describes a HDL synthesis based design methodology that supports user adoption of behavioral-level synthesis into normal design practices. The use of these techniques increases understanding of the HDL descriptions before synthesis, and makes the comparison of pre- and post-synthesis design behavior through simulation much more direct. This(More)
— This paper presents a scalable and low power low-density parity-check (LDPC) decoder design for the next generation wireless handset SoC. The methodology is based on high level synthesis: PICO (program-in chip-out) tool was used to produce efficient RTL directly from a sequential un-timed C algorithm. We propose two parallel LDPC decoder architectures:(More)
Prostaglandin D(2), the ligand for the G protein-coupled receptors DP1 and CRTH2, has been implicated in the pathogenesis of the allergic response in diseases such as asthma, rhinitis, and atopic dermatitis. This prostanoid also fulfills a number of physiological, anti-inflammatory roles through its receptor DP1. We investigated the role of PGD(2) and CRTH2(More)
Prostaglandin D(2) (PGD(2)) and its receptor chemoattractant receptor homologous molecule expressed on T(h)2 cells (CRTH2) have been implicated in the pathogenesis of numerous allergic diseases. We investigated the role of PGD(2) and CRTH2 in allergic cutaneous inflammation by using a highly potent and specific antagonist of CRTH2. Administration of this(More)
Since Rimonabant was withdrawn in Europe in 2008 because of its substantial CNS risk factors including depression and anxiety, the development of anti-obesity drugs targeting CB1R in the brain has been suspended and/or terminated globally. Instead, developing peripherally restricted CB1R antagonists is actively pursued in the hope that not only could they(More)
The discovery of a second receptor for prostaglandin D2, chemoattractant receptor-homologous molecule expressed on T helper type 2 (CRTH2), has revived significant efforts into the development of small-molecule antagonists for allergic diseases as the receptor is predominantly expressed on cells such as eosinophils, TH2 cells and basophils, which are major(More)
A FITC-induced allergic contact hypersensitivity model was used to investigate the role that the prostaglandin D(2) receptor-chemoattractant receptor-homologous molecule expressed on T(h)2 cells (CRTH2) plays in modulating cutaneous inflammation. Our results show that inhibition of CRTH2, achieved via administration of a potent, small molecule antagonist,(More)
Many varied domain experts use Lab VIEW as a graphical system design tool to implement DSP algorithms on myriad target architectures. In this paper, we introduce the latest LabVIEW FPGA compiler that enables domain experts with minimum hardware knowledge to quickly implement, deploy, and verify their domain-specific applications on FPGA hardware. We present(More)
—The increasing data rates expected to be of the order of Gb/s for future wireless systems directly impact the throughput requirements of the modulation and coding subsystems of the physical layer. In an effort to design a suitable channel coding solution for 5G wireless systems, in this brief we present a massively-parallel 2.48Gb/s Quasi-Cyclic(More)