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Resistin (RETN), recently found to be relevant to inflammation and inflammatory disorders. We, therefore, aimed to investigate the potential role of RETN gene polymorphism in pathogenesis of acne vulgaris with familial history. We investigated the RETN-420C/G polymorphism in 180 patients with acne vulgaris and 180 healthy individuals in a case-control(More)
Advances in communication technologies have made it easier to distribute and communicate information effectively. The world has become a global village with the advent of the Internet. Besides getting the benefits of information technology, the world faces threats of violations of copyright, digital counterfeiting, privacy and plagiarism. These issues have(More)
Nowadays, with the extensive use of internet all over the world, most of the government, public and private data are increasingly being published on internet. The protection of these online documents is the need of the hour and need to be dealt with urgently. Text watermarking is the technique which helps to protect the authenticity and integrity of text(More)
OBJECTIVE To assess the use, handling and disposal of insulin injection equipment by diabetic patients in Pakistan. METHODS We conducted a cross-sectional study at diabetic clinics in five tertiary centers in Pakistan. All diabetic patients (type 1/type 2) who were on insulin for more than 1 month, were included. An Urdu (local language)-translated(More)
A case-control and trio-families study was performed to establish a potential association between TNF-alpha gene promoter SNPs at -308 and -238, and occurrence of CAD in a Pakistani population. In the first phase, 150 patients and 150 controls were enrolled in the case-control association study. In the second phase, heritability of susceptible alleles was(More)
Interleukin-8 (IL-8) is a well-known inflammatory chemokine and suggested to be involved in the development of acne vulgaris. This study investigates IL-8 plasma levels in acne patients and healthy controls and the molecular basis for the regulation of the IL-8 gene in a Pakistani population. Patients with acne vulgaris (n = 264) and healthy individuals (n(More)
Biallelic mutations in IGHMBP2 cause spinal muscular atrophy with respiratory distress type 1 (SMARD1) or Charcot-Marie-Tooth type 2S (CMT2S). We report three families variably affected by IGHMBP2 mutations. Patient 1, an 8-year-old boy with two homozygous variants: c.2T>C and c.861C>G, was wheelchair bound due to sensorimotor axonal neuropathy and chronic(More)
Total Quality Management (TQM) is a unified organizational setting to improve the quality at every function and level of organization. The objective of this study is to measure the effect of TQM practices on the performance of the telecom sector of Pakistan. Telecom sector is continuously striving to improve the quality of its services to achieve business(More)
MIMO technology is one of the smart antenna technologies that support employment of large number of antennas at both transmitting and receiving side. The need of high transmission rate in communication systems can be accomplished by bringing into this technology. Consequently, in contemporary communication systems it can play a vital role that can achieve(More)