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PURPOSE To evaluate the efficacy of amniotic membrane transplantation in the management of treated infectious corneal ulcer in which inflammatory reactions were responsible for corneal damage. METHOD A prospective study of 21 consecutive eyes (21 patients) was performed. Sufficient antibacterial, antifungal, or antiviral agents were applied to eradicate(More)
We performed one-step procedures of photorefractive keratectomy (PRK) with the use of the excimer laser (193 nm) on 1519 myopic eyes during 1 year. From this group, we prospectively evaluated visual and refractive results of 202 (13%) consecutive myopic eyes that were followed for more than 1 year. Myopic eyes were divided into two groups according to the(More)
In the present study, we investigated the effect of adenosine triphosphate (ATP) on cytosolic free calcium mobilization and mitogenic activity in cultured bovine corneal endothelial cells (BCEC). The [Ca2+]i was determined using a Ca2+ sensitive indicator, Fura-2/AM, and cell proliferation was evaluated by counting the cell number. ATP, its metabolites and(More)
We evaluated the clinical results of excimer laser photorefractive keratectomy (PRK) on 18 myopic eyes of 13 patients with residual myopia after radial keratotomy. Follow up was 24 months or more and the time interval between radial keratotomy and PRK ranged from 12 to 94 months. Patients were divided into two groups for analysis based on their preoperative(More)
To determine the expression of matrix metalloproteinases (MMPs) in cornea following excimer laser keratectomy, two sets of experiments were performed. In the first experiment, disciform excimer keratectomy was performed on rat corneas. The central regenerating epithelium was harvested at 3-96 h postwounding. MMP levels were assayed in the regenerated(More)
BACKGROUND AND OBJECTIVE Excimer laser-corneal tissue interaction liberates highly reactive free radicals. Our aim was to determine if intraoperative application of antioxidants reduces the postoperative corneal light scattering by minimizing free radical-mediated cellular injury. STUDY DESIGN/MATERIALS AND METHODS Phototherapeutic keratectomy (PTK) was(More)
The maximum myopic correction with one-step ablation in excimer laser photorefractive keratectomy (PRK) using the ExciMed UV200 LA 193-nanometer excimer laser (Summit Technology, Inc, Waltham, Mass,) is only up to 6.00 D because of a fixed computer program. We performed a simultaneous two-step PRK procedure for nearly full correction on 19 eyes of 19(More)
PURPOSE To evaluate the long-term stability, complications, and causative factors in eyes that had photorefractive keratectomy (PRK) for myopia. SETTING Kangnam St. Mary's Hospital, Seoul, Korea. METHODS This study evaluated the results of PRK in 201 myopic eyes with a consecutive 5 year follow-up. Preoperative myopia ranged from 2.25 to 12.50 diopters(More)
PURPOSE To report four cases of Acanthamoeba keratitis related to the overnight wearing of orthokeratology lenses. METHODS Four patients had histories of overnight wearing of orthokeratology lenses when they presented with corneal ulcers. They had used a contact lens care system irregularly with tap water. RESULTS The organism isolated by corneal(More)
Acanthamoeba keratitis is uncommon, but one of the most severe infectious diseases of the cornea. Delayed diagnosis or misdiagnosis as bacterial or herpes simplex keratitis leads to extensive corneal inflammation and profound visual loss. Therefore, accurate and rapid diagnosis of Acanthamoeba keratitis is essential for successful treatment and good(More)